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Impaired clearance of apoptotic cells leads to HMGB1 release in the bone marrow of patients with myelodysplastic syndromes and induces TLR4-mediated cytokine production.
Velegraki M, Papakonstanti E, Mavroudi I, Psyllaki M, Tsatsanis C, Oulas A, Iliopoulos I, Katonis P, Papadaki HA. Velegraki M, et al. Among authors: psyllaki m. Haematologica. 2013 Aug;98(8):1206-15. doi: 10.3324/haematol.2012.064642. Epub 2013 Feb 12. Haematologica. 2013. PMID: 23403315 Free PMC article.
Two patients with nonimmune chronic idiopathic neutropenia of adults developing acute myeloid leukemia with aberrant phenotype and complex karyotype but no mutations in granulocyte colony-stimulating factor receptor.
Papadaki HA, Kosteas T, Gemetzi C, Alexandrakis M, Psyllaki M, Eliopoulos GD. Papadaki HA, et al. Among authors: psyllaki m. Ann Hematol. 2002 Jan;81(1):50-4. doi: 10.1007/s00277-001-0401-z. Epub 2001 Dec 14. Ann Hematol. 2002. PMID: 11807637
Alendronate reduces serum TNFalpha and IL-1beta, increases neutrophil counts, and improves bone mineral density and bone metabolism indices in patients with chronic idiopathic neutropenia (CIN)-associated osteopenia/osteoporosis.
Papadaki HA, Tsatsanis C, Christoforidou A, Malliaraki N, Psyllaki M, Pontikoglou C, Miliaki M, Margioris AN, Eliopoulos GD. Papadaki HA, et al. Among authors: psyllaki m. J Bone Miner Metab. 2004;22(6):577-87. doi: 10.1007/s00774-004-0526-y. J Bone Miner Metab. 2004. PMID: 15490268 Clinical Trial.
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