Cullinane C - Search Results

1

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.

Shortt J, Martin BP, Newbold A, Hannan KM, Devlin JR, Baker AJ, Ralli R, Cullinane C, Schmitt CA, Reimann M, Hall MN, Wall M, Hannan RD, Pearson RB, McArthur GA, Johnstone RW. Shortt J, et al. Among authors: cullinane c. Blood. 2013 Apr 11;121(15):2964-74. doi: 10.1182/blood-2012-08-446096. Epub 2013 Feb 12. Blood. 2013. PMID: 23403624 Free PMC article.

2

EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor.

Solomon B, Hagekyriakou J, Trivett MK, Stacker SA, McArthur GA, Cullinane C. Solomon B, et al. Among authors: cullinane c. Int J Radiat Oncol Biol Phys. 2003 Mar 1;55(3):713-23. doi: 10.1016/s0360-3016(02)04357-2. Int J Radiat Oncol Biol Phys. 2003. PMID: 12573759

3

Applications of positron emission tomography in the development of molecular targeted cancer therapeutics.

Solomon B, McArthur G, Cullinane C, Zalcberg J, Hicks R. Solomon B, et al. Among authors: cullinane c. BioDrugs. 2003;17(5):339-54. doi: 10.2165/00063030-200317050-00004. BioDrugs. 2003. PMID: 14498764 Review.

4

Modulation of intratumoral hypoxia by the epidermal growth factor receptor inhibitor gefitinib detected using small animal PET imaging.

Solomon B, Binns D, Roselt P, Weibe LI, McArthur GA, Cullinane C, Hicks RJ. Solomon B, et al. Among authors: cullinane c. Mol Cancer Ther. 2005 Sep;4(9):1417-22. doi: 10.1158/1535-7163.MCT-05-0066. Mol Cancer Ther. 2005. PMID: 16170034

5

An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development.

Cullinane C, Dorow DS, Kansara M, Conus N, Binns D, Hicks RJ, Ashman LK, McArthur GA, Thomas DM. Cullinane C, et al. Cancer Res. 2005 Nov 1;65(21):9633-6. doi: 10.1158/0008-5472.CAN-05-2285. Cancer Res. 2005. PMID: 16266981 Free article.

6

Multi-tracer small animal PET imaging of the tumour response to the novel pan-Erb-B inhibitor CI-1033.

Dorow DS, Cullinane C, Conus N, Roselt P, Binns D, McCarthy TJ, McArthur GA, Hicks RJ. Dorow DS, et al. Among authors: cullinane c. Eur J Nucl Med Mol Imaging. 2006 Apr;33(4):441-52. doi: 10.1007/s00259-005-0039-5. Epub 2006 Feb 1. Eur J Nucl Med Mol Imaging. 2006. PMID: 16450138

7

Preclinical evaluation of nilotinib efficacy in an imatinib-resistant KIT-driven tumor model.

Cullinane C, Natoli A, Hui Y, Conus N, Jackson S, Brüggen J, Manley PW, McArthur GA. Cullinane C, et al. Mol Cancer Ther. 2010 May;9(5):1461-8. doi: 10.1158/1535-7163.MCT-09-1181. Epub 2010 May 4. Mol Cancer Ther. 2010. PMID: 20442311

8

18F-FLT PET as a surrogate marker of drug efficacy during mTOR inhibition by everolimus in a preclinical cisplatin-resistant ovarian tumor model.

Aide N, Kinross K, Cullinane C, Roselt P, Waldeck K, Neels O, Dorow D, McArthur G, Hicks RJ. Aide N, et al. Among authors: cullinane c. J Nucl Med. 2010 Oct;51(10):1559-64. doi: 10.2967/jnumed.109.073288. Epub 2010 Sep 16. J Nucl Med. 2010. PMID: 20847160 Free article.

9

In vivo activity of combined PI3K/mTOR and MEK inhibition in a Kras(G12D);Pten deletion mouse model of ovarian cancer.

Kinross KM, Brown DV, Kleinschmidt M, Jackson S, Christensen J, Cullinane C, Hicks RJ, Johnstone RW, McArthur GA. Kinross KM, et al. Among authors: cullinane c. Mol Cancer Ther. 2011 Aug;10(8):1440-9. doi: 10.1158/1535-7163.MCT-11-0240. Epub 2011 Jun 1. Mol Cancer Ther. 2011. PMID: 21632463

10

Differential (18)F-FDG and 3'-deoxy-3'-(18)F-fluorothymidine PET responses to pharmacologic inhibition of the c-MET receptor in preclinical tumor models.

Cullinane C, Dorow DS, Jackson S, Solomon B, Bogatyreva E, Binns D, Young R, Arango ME, Christensen JG, McArthur GA, Hicks RJ. Cullinane C, et al. J Nucl Med. 2011 Aug;52(8):1261-7. doi: 10.2967/jnumed.110.086967. Epub 2011 Jul 15. J Nucl Med. 2011. PMID: 21764800 Free article.

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