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Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Shortt J, Martin BP, Newbold A, Hannan KM, Devlin JR, Baker AJ, Ralli R, Cullinane C, Schmitt CA, Reimann M, Hall MN, Wall M, Hannan RD, Pearson RB, McArthur GA, Johnstone RW. Shortt J, et al. Among authors: hall mn. Blood. 2013 Apr 11;121(15):2964-74. doi: 10.1182/blood-2012-08-446096. Epub 2013 Feb 12. Blood. 2013. PMID: 23403624 Free PMC article.
Maximizing the Efficacy of MAPK-Targeted Treatment in PTENLOF/BRAFMUT Melanoma through PI3K and IGF1R Inhibition.
Herkert B, Kauffmann A, Mollé S, Schnell C, Ferrat T, Voshol H, Juengert J, Erasimus H, Marszalek G, Kazic-Legueux M, Billy E, Ruddy D, Stump M, Guthy D, Ristov M, Calkins K, Maira SM, Sellers WR, Hofmann F, Hall MN, Brachmann SM. Herkert B, et al. Among authors: hall mn. Cancer Res. 2016 Jan 15;76(2):390-402. doi: 10.1158/0008-5472.CAN-14-3358. Epub 2015 Nov 17. Cancer Res. 2016. PMID: 26577700
mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR.
Battaglioni S, Craigie LM, Filippini S, Maier T, Hall MN. Battaglioni S, et al. Among authors: hall mn. Proc Natl Acad Sci U S A. 2024 Aug 20;121(34):e2405959121. doi: 10.1073/pnas.2405959121. Epub 2024 Aug 14. Proc Natl Acad Sci U S A. 2024. PMID: 39141345 Free PMC article.
ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR inhibition.
Borenäs M, Umapathy G, Lind DE, Lai WY, Guan J, Johansson J, Jennische E, Schmidt A, Kurhe Y, Gabre JL, Aniszewska A, Strömberg A, Bemark M, Hall MN, Eynden JVD, Hallberg B, Palmer RH. Borenäs M, et al. Among authors: hall mn. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2315242121. doi: 10.1073/pnas.2315242121. Epub 2023 Dec 28. Proc Natl Acad Sci U S A. 2024. PMID: 38154064 Free PMC article.
347 results