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Page 1
Nomenclature for alleles of the thiopurine methyltransferase gene.
Appell ML, Berg J, Duley J, Evans WE, Kennedy MA, Lennard L, Marinaki T, McLeod HL, Relling MV, Schaeffeler E, Schwab M, Weinshilboum R, Yeoh AE, McDonagh EM, Hebert JM, Klein TE, Coulthard SA. Appell ML, et al. Among authors: weinshilboum r. Pharmacogenet Genomics. 2013 Apr;23(4):242-8. doi: 10.1097/FPC.0b013e32835f1cc0. Pharmacogenet Genomics. 2013. PMID: 23407052 Free PMC article.
Very important pharmacogene summary: thiopurine S-methyltransferase.
Wang L, Pelleymounter L, Weinshilboum R, Johnson JA, Hebert JM, Altman RB, Klein TE. Wang L, et al. Among authors: weinshilboum r. Pharmacogenet Genomics. 2010 Jun;20(6):401-5. doi: 10.1097/FPC.0b013e3283352860. Pharmacogenet Genomics. 2010. PMID: 20154640 Free PMC article. Review. No abstract available.
Very important pharmacogene summary: sulfotransferase 1A1.
Hildebrandt M, Adjei A, Weinshilboum R, Johnson JA, Berlin DS, Klein TE, Altman RB. Hildebrandt M, et al. Among authors: weinshilboum r. Pharmacogenet Genomics. 2009 Jun;19(6):404-6. doi: 10.1097/FPC.0b013e32832e042e. Pharmacogenet Genomics. 2009. PMID: 19451861 Review. No abstract available.
Genome-wide association studies in pharmacogenomics: successes and lessons.
Motsinger-Reif AA, Jorgenson E, Relling MV, Kroetz DL, Weinshilboum R, Cox NJ, Roden DM. Motsinger-Reif AA, et al. Among authors: weinshilboum r. Pharmacogenet Genomics. 2013 Aug;23(8):383-94. doi: 10.1097/FPC.0b013e32833d7b45. Pharmacogenet Genomics. 2013. PMID: 20639796 Free PMC article. Review.
Human thiopurine methyltransferase pharmacogenetics: gene sequence polymorphisms.
Otterness D, Szumlanski C, Lennard L, Klemetsdal B, Aarbakke J, Park-Hah JO, Iven H, Schmiegelow K, Branum E, O'Brien J, Weinshilboum R. Otterness D, et al. Among authors: weinshilboum r. Clin Pharmacol Ther. 1997 Jul;62(1):60-73. doi: 10.1016/S0009-9236(97)90152-1. Clin Pharmacol Ther. 1997. PMID: 9246020
Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies.
Tamm R, Mägi R, Tremmel R, Winter S, Mihailov E, Smid A, Möricke A, Klein K, Schrappe M, Stanulla M, Houlston R, Weinshilboum R, Mlinarič Raščan I, Metspalu A, Milani L, Schwab M, Schaeffeler E. Tamm R, et al. Among authors: weinshilboum r. Clin Pharmacol Ther. 2017 May;101(5):684-695. doi: 10.1002/cpt.540. Epub 2017 Feb 1. Clin Pharmacol Ther. 2017. PMID: 27770449 Free PMC article. Review.
Antiestrogen pathway (aromatase inhibitor).
Desta Z, Nguyen A, Flockhart D, Skaar T, Fletcher R, Weinshilboum R, Berlin DS, Klein TE, Altman RB. Desta Z, et al. Among authors: weinshilboum r. Pharmacogenet Genomics. 2009 Jul;19(7):554-5. doi: 10.1097/FPC.0b013e32832e0ec1. Pharmacogenet Genomics. 2009. PMID: 19512956 Free PMC article. No abstract available.
Research Directions in the Clinical Implementation of Pharmacogenomics: An Overview of US Programs and Projects.
Volpi S, Bult CJ, Chisholm RL, Deverka PA, Ginsburg GS, Jacob HJ, Kasapi M, McLeod HL, Roden DM, Williams MS, Green ED, Rodriguez LL, Aronson S, Cavallari LH, Denny JC, Dressler LG, Johnson JA, Klein TE, Leeder JS, Piquette-Miller M, Perera M, Rasmussen-Torvik LJ, Rehm HL, Ritchie MD, Skaar TC, Wagle N, Weinshilboum R, Weitzel KW, Wildin R, Wilson J, Manolio TA, Relling MV. Volpi S, et al. Among authors: weinshilboum r. Clin Pharmacol Ther. 2018 May;103(5):778-786. doi: 10.1002/cpt.1048. Epub 2018 Mar 30. Clin Pharmacol Ther. 2018. PMID: 29460415 Free PMC article. Review.
549 results