Weihl CC - Search Results

1

Monitoring autophagy in the treatment of protein aggregate diseases: steps toward identifying autophagic biomarkers.

Weihl CC. Weihl CC. Neurotherapeutics. 2013 Jul;10(3):383-90. doi: 10.1007/s13311-013-0180-y. Neurotherapeutics. 2013. PMID: 23408309 Free PMC article. Review.

2

Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease.

Ju JS, Miller SE, Hanson PI, Weihl CC. Ju JS, et al. Among authors: weihl cc. J Biol Chem. 2008 Oct 31;283(44):30289-99. doi: 10.1074/jbc.M805517200. Epub 2008 Aug 20. J Biol Chem. 2008. PMID: 18715868 Free PMC article.

3

Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters.

Ju JS, Miller SE, Jackson E, Cadwell K, Piwnica-Worms D, Weihl CC. Ju JS, et al. Among authors: weihl cc. Autophagy. 2009 May;5(4):511-9. doi: 10.4161/auto.5.4.7761. Epub 2009 May 6. Autophagy. 2009. PMID: 19305149 Free PMC article.

4

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease.

Ju JS, Fuentealba RA, Miller SE, Jackson E, Piwnica-Worms D, Baloh RH, Weihl CC. Ju JS, et al. Among authors: weihl cc. J Cell Biol. 2009 Dec 14;187(6):875-88. doi: 10.1083/jcb.200908115. J Cell Biol. 2009. PMID: 20008565 Free PMC article.

5

Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy.

Ju JS, Weihl CC. Ju JS, et al. Among authors: weihl cc. Hum Mol Genet. 2010 Apr 15;19(R1):R38-45. doi: 10.1093/hmg/ddq157. Epub 2010 Apr 21. Hum Mol Genet. 2010. PMID: 20410287 Free PMC article. Review.

6

Quantitation of "autophagic flux" in mature skeletal muscle.

Ju JS, Varadhachary AS, Miller SE, Weihl CC. Ju JS, et al. Among authors: weihl cc. Autophagy. 2010 Oct;6(7):929-35. doi: 10.4161/auto.6.7.12785. Epub 2010 Oct 24. Autophagy. 2010. PMID: 20657169 Free PMC article.

7

Sporadic inclusion body myositis: possible pathogenesis inferred from biomarkers.

Weihl CC, Pestronk A. Weihl CC, et al. Curr Opin Neurol. 2010 Oct;23(5):482-8. doi: 10.1097/WCO.0b013e32833d3897. Curr Opin Neurol. 2010. PMID: 20664349 Free PMC article. Review.

8

Valosin containing protein associated fronto-temporal lobar degeneration: clinical presentation, pathologic features and pathogenesis.

Weihl CC. Weihl CC. Curr Alzheimer Res. 2011 May;8(3):252-60. doi: 10.2174/156720511795563773. Curr Alzheimer Res. 2011. PMID: 21222596 Free PMC article. Review.

9

An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors.

Fuentealba RA, Marasa J, Diamond MI, Piwnica-Worms D, Weihl CC. Fuentealba RA, et al. Among authors: weihl cc. Hum Mol Genet. 2012 Feb 1;21(3):664-80. doi: 10.1093/hmg/ddr500. Epub 2011 Nov 3. Hum Mol Genet. 2012. PMID: 22052286 Free PMC article.

10

mTOR dysfunction contributes to vacuolar pathology and weakness in valosin-containing protein associated inclusion body myopathy.

Ching JK, Elizabeth SV, Ju JS, Lusk C, Pittman SK, Weihl CC. Ching JK, et al. Among authors: weihl cc. Hum Mol Genet. 2013 Mar 15;22(6):1167-79. doi: 10.1093/hmg/dds524. Epub 2012 Dec 18. Hum Mol Genet. 2013. PMID: 23250913 Free PMC article.

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