Tehan B - Search Results

1

Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy.

Bennett KA, Tehan B, Lebon G, Tate CG, Weir M, Marshall FH, Langmead CJ. Bennett KA, et al. Among authors: tehan b. Mol Pharmacol. 2013 May;83(5):949-58. doi: 10.1124/mol.112.084509. Epub 2013 Feb 19. Mol Pharmacol. 2013. PMID: 23429888 Free PMC article.

2

Mutagenic mapping suggests a novel binding mode for selective agonists of M1 muscarinic acetylcholine receptors.

Lebon G, Langmead CJ, Tehan BG, Hulme EC. Lebon G, et al. Mol Pharmacol. 2009 Feb;75(2):331-41. doi: 10.1124/mol.108.050963. Epub 2008 Nov 11. Mol Pharmacol. 2009. PMID: 19001633 Free PMC article.

3

Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine.

Doré AS, Robertson N, Errey JC, Ng I, Hollenstein K, Tehan B, Hurrell E, Bennett K, Congreve M, Magnani F, Tate CG, Weir M, Marshall FH. Doré AS, et al. Among authors: tehan b. Structure. 2011 Sep 7;19(9):1283-93. doi: 10.1016/j.str.2011.06.014. Structure. 2011. PMID: 21885291 Free PMC article.

4

Biophysical mapping of the adenosine A2A receptor.

Zhukov A, Andrews SP, Errey JC, Robertson N, Tehan B, Mason JS, Marshall FH, Weir M, Congreve M. Zhukov A, et al. Among authors: tehan b. J Med Chem. 2011 Jul 14;54(13):4312-23. doi: 10.1021/jm2003798. Epub 2011 Jun 10. J Med Chem. 2011. PMID: 21661720 Free PMC article.

5

Discovery of 1,2,4-triazine derivatives as adenosine A(2A) antagonists using structure based drug design.

Congreve M, Andrews SP, Doré AS, Hollenstein K, Hurrell E, Langmead CJ, Mason JS, Ng IW, Tehan B, Zhukov A, Weir M, Marshall FH. Congreve M, et al. Among authors: tehan b. J Med Chem. 2012 Mar 8;55(5):1898-903. doi: 10.1021/jm201376w. Epub 2012 Jan 27. J Med Chem. 2012. PMID: 22220592 Free PMC article.

6

Roof and floor of the muscarinic binding pocket: variations in the binding modes of orthosteric ligands.

Goodwin JA, Hulme EC, Langmead CJ, Tehan BG. Goodwin JA, et al. Mol Pharmacol. 2007 Dec;72(6):1484-96. doi: 10.1124/mol.107.038265. Epub 2007 Sep 11. Mol Pharmacol. 2007. PMID: 17848601

7

Orthosteric and allosteric modes of interaction of novel selective agonists of the M1 muscarinic acetylcholine receptor.

Avlani VA, Langmead CJ, Guida E, Wood MD, Tehan BG, Herdon HJ, Watson JM, Sexton PM, Christopoulos A. Avlani VA, et al. Mol Pharmacol. 2010 Jul;78(1):94-104. doi: 10.1124/mol.110.064345. Epub 2010 Apr 22. Mol Pharmacol. 2010. PMID: 20413650

8

Pharmacology and physiology of gastrointestinal enteroendocrine cells.

Mace OJ, Tehan B, Marshall F. Mace OJ, et al. Among authors: tehan b. Pharmacol Res Perspect. 2015 Aug;3(4):e00155. doi: 10.1002/prp2.155. Epub 2015 Jul 7. Pharmacol Res Perspect. 2015. PMID: 26213627 Free PMC article. Review.

9

Unifying family A GPCR theories of activation.

Tehan BG, Bortolato A, Blaney FE, Weir MP, Mason JS. Tehan BG, et al. Pharmacol Ther. 2014 Jul;143(1):51-60. doi: 10.1016/j.pharmthera.2014.02.004. Epub 2014 Feb 19. Pharmacol Ther. 2014. PMID: 24561131 Review.

10

Structure of Class B GPCRs: new horizons for drug discovery.

Bortolato A, Doré AS, Hollenstein K, Tehan BG, Mason JS, Marshall FH. Bortolato A, et al. Br J Pharmacol. 2014 Jul;171(13):3132-45. doi: 10.1111/bph.12689. Br J Pharmacol. 2014. PMID: 24628305 Free PMC article. Review.

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