Grütter MG - Search Results

1

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters.

Dreier B, Honegger A, Hess C, Nagy-Davidescu G, Mittl PR, Grütter MG, Belousova N, Mikheeva G, Krasnykh V, Plückthun A. Dreier B, et al. Among authors: grutter mg. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):E869-77. doi: 10.1073/pnas.1213653110. Epub 2013 Feb 19. Proc Natl Acad Sci U S A. 2013. PMID: 23431166 Free PMC article.

2

The crystal structure of metal-free human EF-hand protein S100A3 at 1.7-A resolution.

Fritz G, Mittl PR, Vasak M, Grutter MG, Heizmann CW. Fritz G, et al. Among authors: grutter mg. J Biol Chem. 2002 Sep 6;277(36):33092-8. doi: 10.1074/jbc.M200574200. Epub 2002 Jun 3. J Biol Chem. 2002. PMID: 12045193 Free article.

3

Designed to be stable: crystal structure of a consensus ankyrin repeat protein.

Kohl A, Binz HK, Forrer P, Stumpp MT, Plückthun A, Grütter MG. Kohl A, et al. Among authors: grutter mg. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1700-5. doi: 10.1073/pnas.0337680100. Epub 2003 Feb 3. Proc Natl Acad Sci U S A. 2003. PMID: 12566564 Free PMC article.

4

The crystal structure of Helicobacter cysteine-rich protein C at 2.0 A resolution: similar peptide-binding sites in TPR and SEL1-like repeat proteins.

Lüthy L, Grütter MG, Mittl PR. Lüthy L, et al. Among authors: grutter mg. J Mol Biol. 2004 Jul 16;340(4):829-41. doi: 10.1016/j.jmb.2004.04.055. J Mol Biol. 2004. PMID: 15223324

5

Opportunities for structure-based design of protease-directed drugs.

Mittl PR, Grütter MG. Mittl PR, et al. Among authors: grutter mg. Curr Opin Struct Biol. 2006 Dec;16(6):769-75. doi: 10.1016/j.sbi.2006.10.014. Epub 2006 Nov 16. Curr Opin Struct Biol. 2006. PMID: 17112720 Review.

6

Stabilizing ionic interactions in a full-consensus ankyrin repeat protein.

Merz T, Wetzel SK, Firbank S, Plückthun A, Grütter MG, Mittl PR. Merz T, et al. Among authors: grutter mg. J Mol Biol. 2008 Feb 8;376(1):232-40. doi: 10.1016/j.jmb.2007.11.047. Epub 2007 Nov 22. J Mol Biol. 2008. PMID: 18155045

7

Structural determinants for improved stability of designed ankyrin repeat proteins with a redesigned C-capping module.

Kramer MA, Wetzel SK, Plückthun A, Mittl PR, Grütter MG. Kramer MA, et al. Among authors: grutter mg. J Mol Biol. 2010 Dec 3;404(3):381-91. doi: 10.1016/j.jmb.2010.09.023. Epub 2010 Sep 17. J Mol Biol. 2010. PMID: 20851127

8

In silico identification and crystal structure validation of caspase-3 inhibitors without a P1 aspartic acid moiety.

Ganesan R, Jelakovic S, Mittl PR, Caflisch A, Grütter MG. Ganesan R, et al. Among authors: grutter mg. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Aug 1;67(Pt 8):842-50. doi: 10.1107/S1744309111018604. Epub 2011 Jul 13. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011. PMID: 21821879 Free PMC article.

9

Structure-based optimization of designed Armadillo-repeat proteins.

Madhurantakam C, Varadamsetty G, Grütter MG, Plückthun A, Mittl PR. Madhurantakam C, et al. Among authors: grutter mg. Protein Sci. 2012 Jul;21(7):1015-28. doi: 10.1002/pro.2085. Epub 2012 May 24. Protein Sci. 2012. PMID: 22544642 Free PMC article.

10

Specific inhibition of caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors.

Schroeder T, Barandun J, Flütsch A, Briand C, Mittl PR, Grütter MG. Schroeder T, et al. Among authors: grutter mg. Structure. 2013 Feb 5;21(2):277-89. doi: 10.1016/j.str.2012.12.011. Epub 2013 Jan 17. Structure. 2013. PMID: 23333429 Free article.

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