Brekken RA - Search Results

1

Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.

Chatterjee S, Heukamp LC, Siobal M, Schöttle J, Wieczorek C, Peifer M, Frasca D, Koker M, König K, Meder L, Rauh D, Buettner R, Wolf J, Brekken RA, Neumaier B, Christofori G, Thomas RK, Ullrich RT. Chatterjee S, et al. Among authors: brekken ra. J Clin Invest. 2013 Apr;123(4):1732-40. doi: 10.1172/JCI65385. J Clin Invest. 2013. PMID: 23454747 Free PMC article.

2

Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A.

Nozaki M, Sakurai E, Raisler BJ, Baffi JZ, Witta J, Ogura Y, Brekken RA, Sage EH, Ambati BK, Ambati J. Nozaki M, et al. Among authors: brekken ra. J Clin Invest. 2006 Feb;116(2):422-9. doi: 10.1172/JCI26316. J Clin Invest. 2006. PMID: 16453023 Free PMC article.

3

Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy.

D'Amico G, Korhonen EA, Anisimov A, Zarkada G, Holopainen T, Hägerling R, Kiefer F, Eklund L, Sormunen R, Elamaa H, Brekken RA, Adams RH, Koh GY, Saharinen P, Alitalo K. D'Amico G, et al. Among authors: brekken ra. J Clin Invest. 2014 Feb;124(2):824-34. doi: 10.1172/JCI68897. Epub 2014 Jan 16. J Clin Invest. 2014. PMID: 24430181 Free PMC article.

4

Autocrine VEGF-VEGF-R loop on podocytes during glomerulonephritis in humans.

Hohenstein B, Colin M, Foellmer C, Amann KU, Brekken RA, Daniel C, Hugo CP. Hohenstein B, et al. Among authors: brekken ra. Nephrol Dial Transplant. 2010 Oct;25(10):3170-80. doi: 10.1093/ndt/gfq200. Epub 2010 Apr 15. Nephrol Dial Transplant. 2010. PMID: 20395257

5

Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma.

Aguilera KY, Rivera LB, Hur H, Carbon JG, Toombs JE, Goldstein CD, Dellinger MT, Castrillon DH, Brekken RA. Aguilera KY, et al. Among authors: brekken ra. Cancer Res. 2014 Feb 15;74(4):1032-44. doi: 10.1158/0008-5472.CAN-13-2800. Epub 2013 Dec 17. Cancer Res. 2014. PMID: 24346431 Free PMC article.

6

Loss of SPARC in bladder cancer enhances carcinogenesis and progression.

Said N, Frierson HF, Sanchez-Carbayo M, Brekken RA, Theodorescu D. Said N, et al. Among authors: brekken ra. J Clin Invest. 2013 Feb;123(2):751-66. doi: 10.1172/JCI64782. Epub 2013 Jan 16. J Clin Invest. 2013. PMID: 23321672 Free PMC article.

7

Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice.

Chambliss KL, Wu Q, Oltmann S, Konaniah ES, Umetani M, Korach KS, Thomas GD, Mineo C, Yuhanna IS, Kim SH, Madak-Erdogan Z, Maggi A, Dineen SP, Roland CL, Hui DY, Brekken RA, Katzenellenbogen JA, Katzenellenbogen BS, Shaul PW. Chambliss KL, et al. Among authors: brekken ra. J Clin Invest. 2010 Jul;120(7):2319-30. doi: 10.1172/JCI38291. Epub 2010 Jun 23. J Clin Invest. 2010. PMID: 20577047 Free PMC article.

8

LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment.

Peña CG, Nakada Y, Saatcioglu HD, Aloisio GM, Cuevas I, Zhang S, Miller DS, Lea JS, Wong KK, DeBerardinis RJ, Amelio AL, Brekken RA, Castrillon DH. Peña CG, et al. Among authors: brekken ra. J Clin Invest. 2015 Nov 2;125(11):4063-76. doi: 10.1172/JCI82152. Epub 2015 Sep 28. J Clin Invest. 2015. PMID: 26413869 Free PMC article.

9

Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM.

Brekken RA, Puolakkainen P, Graves DC, Workman G, Lubkin SR, Sage EH. Brekken RA, et al. J Clin Invest. 2003 Feb;111(4):487-95. doi: 10.1172/JCI16804. J Clin Invest. 2003. PMID: 12588887 Free PMC article.

10

Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium.

Dellinger MT, Brekken RA. Dellinger MT, et al. Among authors: brekken ra. PLoS One. 2011;6(12):e28947. doi: 10.1371/journal.pone.0028947. Epub 2011 Dec 12. PLoS One. 2011. PMID: 22174934 Free PMC article.

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