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Blockade of individual Notch ligands and receptors controls graft-versus-host disease.
Tran IT, Sandy AR, Carulli AJ, Ebens C, Chung J, Shan GT, Radojcic V, Friedman A, Gridley T, Shelton A, Reddy P, Samuelson LC, Yan M, Siebel CW, Maillard I. Tran IT, et al. Among authors: gridley t. J Clin Invest. 2013 Apr;123(4):1590-604. doi: 10.1172/JCI65477. J Clin Invest. 2013. PMID: 23454750 Free PMC article.
Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength.
Van de Walle I, Waegemans E, De Medts J, De Smet G, De Smedt M, Snauwaert S, Vandekerckhove B, Kerre T, Leclercq G, Plum J, Gridley T, Wang T, Koch U, Radtke F, Taghon T. Van de Walle I, et al. Among authors: gridley t. J Exp Med. 2013 Apr 8;210(4):683-97. doi: 10.1084/jem.20121798. Epub 2013 Mar 25. J Exp Med. 2013. PMID: 23530123 Free PMC article. Clinical Trial.
Critical role of endothelial Notch1 signaling in postnatal angiogenesis.
Takeshita K, Satoh M, Ii M, Silver M, Limbourg FP, Mukai Y, Rikitake Y, Radtke F, Gridley T, Losordo DW, Liao JK. Takeshita K, et al. Among authors: gridley t. Circ Res. 2007 Jan 5;100(1):70-8. doi: 10.1161/01.RES.0000254788.47304.6e. Epub 2006 Dec 7. Circ Res. 2007. PMID: 17158336 Free PMC article.
Smooth muscle Notch1 mediates neointimal formation after vascular injury.
Li Y, Takeshita K, Liu PY, Satoh M, Oyama N, Mukai Y, Chin MT, Krebs L, Kotlikoff MI, Radtke F, Gridley T, Liao JK. Li Y, et al. Among authors: gridley t. Circulation. 2009 May 26;119(20):2686-92. doi: 10.1161/CIRCULATIONAHA.108.790485. Epub 2009 May 11. Circulation. 2009. PMID: 19433762 Free PMC article.
Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
Jeannet R, Mastio J, Macias-Garcia A, Oravecz A, Ashworth T, Geimer Le Lay AS, Jost B, Le Gras S, Ghysdael J, Gridley T, Honjo T, Radtke F, Aster JC, Chan S, Kastner P. Jeannet R, et al. Among authors: gridley t. Blood. 2010 Dec 16;116(25):5443-54. doi: 10.1182/blood-2010-05-286658. Epub 2010 Sep 9. Blood. 2010. PMID: 20829372 Free PMC article.
183 results