Chalk AM - Search Results

1

Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

Mutsaers AJ, Ng AJ, Baker EK, Russell MR, Chalk AM, Wall M, Liddicoat BJ, Ho PW, Slavin JL, Goradia A, Martin TJ, Purton LE, Dickins RA, Walkley CR. Mutsaers AJ, et al. Among authors: chalk am. Bone. 2013 Jul;55(1):166-78. doi: 10.1016/j.bone.2013.02.016. Epub 2013 Feb 26. Bone. 2013. PMID: 23486187

2

The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.

Singbrant S, Wall M, Moody J, Karlsson G, Chalk AM, Liddicoat B, Russell MR, Walkley CR, Karlsson S. Singbrant S, et al. Among authors: chalk am. Haematologica. 2014 Apr;99(4):647-55. doi: 10.3324/haematol.2013.093971. Epub 2014 Jan 10. Haematologica. 2014. PMID: 24415629 Free PMC article.

3

The Rothmund-Thomson syndrome helicase RECQL4 is essential for hematopoiesis.

Smeets MF, DeLuca E, Wall M, Quach JM, Chalk AM, Deans AJ, Heierhorst J, Purton LE, Izon DJ, Walkley CR. Smeets MF, et al. Among authors: chalk am. J Clin Invest. 2014 Aug;124(8):3551-65. doi: 10.1172/JCI75334. Epub 2014 Jun 24. J Clin Invest. 2014. PMID: 24960165 Free PMC article.

4

Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo.

Ho PW, Goradia A, Russell MR, Chalk AM, Milley KM, Baker EK, Danks JA, Slavin JL, Walia M, Crimeen-Irwin B, Dickins RA, Martin TJ, Walkley CR. Ho PW, et al. Among authors: chalk am. Oncogene. 2015 May 28;34(22):2922-33. doi: 10.1038/onc.2014.217. Epub 2014 Jul 21. Oncogene. 2015. PMID: 25043296

5

Wnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma.

Baker EK, Taylor S, Gupte A, Chalk AM, Bhattacharya S, Green AC, Martin TJ, Strbenac D, Robinson MD, Purton LE, Walkley CR. Baker EK, et al. Among authors: chalk am. Bone. 2015 Apr;73:223-32. doi: 10.1016/j.bone.2014.12.063. Epub 2015 Jan 5. Bone. 2015. PMID: 25571841 Free article.

6

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma.

Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, Burns C, Huang DC, Dyer MA, Simpson KJ, Walkley CR. Gupte A, et al. Among authors: chalk am. Clin Cancer Res. 2015 Jul 15;21(14):3216-29. doi: 10.1158/1078-0432.CCR-14-3026. Epub 2015 Apr 10. Clin Cancer Res. 2015. PMID: 25862761 Free PMC article.

7

BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells.

Baker EK, Taylor S, Gupte A, Sharp PP, Walia M, Walsh NC, Zannettino AC, Chalk AM, Burns CJ, Walkley CR. Baker EK, et al. Among authors: chalk am. Sci Rep. 2015 May 6;5:10120. doi: 10.1038/srep10120. Sci Rep. 2015. PMID: 25944566 Free PMC article.

8

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself.

Liddicoat BJ, Piskol R, Chalk AM, Ramaswami G, Higuchi M, Hartner JC, Li JB, Seeburg PH, Walkley CR. Liddicoat BJ, et al. Among authors: chalk am. Science. 2015 Sep 4;349(6252):1115-20. doi: 10.1126/science.aac7049. Epub 2015 Jul 23. Science. 2015. PMID: 26275108 Free PMC article.

9

Gene expression profiling to define the cell intrinsic role of the SKI proto-oncogene in hematopoiesis and myeloid neoplasms.

Chalk AM, Liddicoat BJ, Walkley CR, Singbrant S. Chalk AM, et al. Genom Data. 2014 Jul 4;2:189-91. doi: 10.1016/j.gdata.2014.06.022. eCollection 2014 Dec. Genom Data. 2014. PMID: 26484093 Free PMC article.

10

ADAR1, inosine and the immune sensing system: distinguishing self from non-self.

Liddicoat BJ, Chalk AM, Walkley CR. Liddicoat BJ, et al. Among authors: chalk am. Wiley Interdiscip Rev RNA. 2016 Mar-Apr;7(2):157-72. doi: 10.1002/wrna.1322. Epub 2015 Dec 21. Wiley Interdiscip Rev RNA. 2016. PMID: 26692549 Review.

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