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Fibrin facilitates both innate and T cell-mediated defense against Yersinia pestis.
Luo D, Lin JS, Parent MA, Mullarky-Kanevsky I, Szaba FM, Kummer LW, Duso DK, Tighe M, Hill J, Gruber A, Mackman N, Gailani D, Smiley ST. Luo D, et al. Among authors: gruber a. J Immunol. 2013 Apr 15;190(8):4149-61. doi: 10.4049/jimmunol.1203253. Epub 2013 Mar 13. J Immunol. 2013. PMID: 23487423 Free PMC article.
Activated factor XI inhibits chemotaxis of polymorphonuclear leukocytes.
Itakura A, Verbout NG, Phillips KG, Insall RH, Gailani D, Tucker EI, Gruber A, McCarty OJ. Itakura A, et al. Among authors: gruber a. J Leukoc Biol. 2011 Nov;90(5):923-7. doi: 10.1189/jlb.0411182. Epub 2011 Aug 1. J Leukoc Biol. 2011. PMID: 21807745 Free PMC article.
Excess of heme induces tissue factor-dependent activation of coagulation in mice.
Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R. Sparkenbaugh EM, et al. Among authors: gruber a. Haematologica. 2015 Mar;100(3):308-14. doi: 10.3324/haematol.2014.114728. Epub 2015 Jan 16. Haematologica. 2015. PMID: 25596265 Free PMC article.
Factor XI as a Therapeutic Target.
Gailani D, Gruber A. Gailani D, et al. Among authors: gruber a. Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1316-22. doi: 10.1161/ATVBAHA.116.306925. Epub 2016 May 12. Arterioscler Thromb Vasc Biol. 2016. PMID: 27174099 Free PMC article. Review.
1,283 results