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Loss-of-function analyses defines vital and redundant functions of the Plasmodium rhomboid protease family.
Lin JW, Meireles P, Prudêncio M, Engelmann S, Annoura T, Sajid M, Chevalley-Maurel S, Ramesar J, Nahar C, Avramut CM, Koster AJ, Matuschewski K, Waters AP, Janse CJ, Mair GR, Khan SM. Lin JW, et al. Among authors: khan sm. Mol Microbiol. 2013 Apr;88(2):318-38. doi: 10.1111/mmi.12187. Epub 2013 Mar 12. Mol Microbiol. 2013. PMID: 23490234 Free article.
Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility.
van Dijk MR, van Schaijk BC, Khan SM, van Dooren MW, Ramesar J, Kaczanowski S, van Gemert GJ, Kroeze H, Stunnenberg HG, Eling WM, Sauerwein RW, Waters AP, Janse CJ. van Dijk MR, et al. Among authors: khan sm. PLoS Pathog. 2010 Apr 8;6(4):e1000853. doi: 10.1371/journal.ppat.1000853. PLoS Pathog. 2010. PMID: 20386715 Free PMC article.
Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility.
Laurentino EC, Taylor S, Mair GR, Lasonder E, Bartfai R, Stunnenberg HG, Kroeze H, Ramesar J, Franke-Fayard B, Khan SM, Janse CJ, Waters AP. Laurentino EC, et al. Among authors: khan sm. Cell Microbiol. 2011 Dec;13(12):1956-74. doi: 10.1111/j.1462-5822.2011.01683.x. Epub 2011 Oct 14. Cell Microbiol. 2011. PMID: 21899698 Free PMC article.
Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development.
Annoura T, van Schaijk BC, Ploemen IH, Sajid M, Lin JW, Vos MW, Dinmohamed AG, Inaoka DK, Rijpma SR, van Gemert GJ, Chevalley-Maurel S, Kiełbasa SM, Scheltinga F, Franke-Fayard B, Klop O, Hermsen CC, Kita K, Gego A, Franetich JF, Mazier D, Hoffman SL, Janse CJ, Sauerwein RW, Khan SM. Annoura T, et al. Among authors: khan sm. FASEB J. 2014 May;28(5):2158-70. doi: 10.1096/fj.13-241570. Epub 2014 Feb 7. FASEB J. 2014. PMID: 24509910
Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites.
Rijpma SR, van der Velden M, González-Pons M, Annoura T, van Schaijk BC, van Gemert GJ, van den Heuvel JJ, Ramesar J, Chevalley-Maurel S, Ploemen IH, Khan SM, Franetich JF, Mazier D, de Wilt JH, Serrano AE, Russel FG, Janse CJ, Sauerwein RW, Koenderink JB, Franke-Fayard BM. Rijpma SR, et al. Among authors: khan sm. Cell Microbiol. 2016 Mar;18(3):369-83. doi: 10.1111/cmi.12517. Epub 2015 Nov 10. Cell Microbiol. 2016. PMID: 26332724 Free PMC article.
555 results