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Page 1
Loss of Siglec-14 reduces the risk of chronic obstructive pulmonary disease exacerbation.
Angata T, Ishii T, Motegi T, Oka R, Taylor RE, Soto PC, Chang YC, Secundino I, Gao CX, Ohtsubo K, Kitazume S, Nizet V, Varki A, Gemma A, Kida K, Taniguchi N. Angata T, et al. Among authors: ohtsubo k. Cell Mol Life Sci. 2013 Sep;70(17):3199-210. doi: 10.1007/s00018-013-1311-7. Epub 2013 Mar 22. Cell Mol Life Sci. 2013. PMID: 23519826 Free PMC article.
α1,6-Fucosyltransferase (Fut8) is implicated in vulnerability to elastase-induced emphysema in mice and a possible non-invasive predictive marker for disease progression and exacerbations in chronic obstructive pulmonary disease (COPD).
Kamio K, Yoshida T, Gao C, Ishii T, Ota F, Motegi T, Kobayashi S, Fujinawa R, Ohtsubo K, Kitazume S, Angata T, Azuma A, Gemma A, Nishimura M, Betsuyaku T, Kida K, Taniguchi N. Kamio K, et al. Among authors: ohtsubo k. Biochem Biophys Res Commun. 2012 Jul 20;424(1):112-7. doi: 10.1016/j.bbrc.2012.06.081. Epub 2012 Jun 23. Biochem Biophys Res Commun. 2012. PMID: 22732410
Flagellin/Toll-like receptor 5 response was specifically attenuated by keratan sulfate disaccharide via decreased EGFR phosphorylation in normal human bronchial epithelial cells.
Shirato K, Gao C, Ota F, Angata T, Shogomori H, Ohtsubo K, Yoshida K, Lepenies B, Taniguchi N. Shirato K, et al. Among authors: ohtsubo k. Biochem Biophys Res Commun. 2013 Jun 7;435(3):460-5. doi: 10.1016/j.bbrc.2013.05.009. Epub 2013 May 14. Biochem Biophys Res Commun. 2013. PMID: 23680662
A keratan sulfate disaccharide prevents inflammation and the progression of emphysema in murine models.
Gao C, Fujinawa R, Yoshida T, Ueno M, Ota F, Kizuka Y, Hirayama T, Korekane H, Kitazume S, Maeno T, Ohtsubo K, Yoshida K, Yamaguchi Y, Lepenies B, Aretz J, Rademacher C, Kabata H, Hegab AE, Seeberger PH, Betsuyaku T, Kida K, Taniguchi N. Gao C, et al. Among authors: ohtsubo k. Am J Physiol Lung Cell Mol Physiol. 2017 Feb 1;312(2):L268-L276. doi: 10.1152/ajplung.00151.2016. Epub 2016 Dec 23. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28011617 Free article.
A single dose of lipopolysaccharide into mice with emphysema mimics human chronic obstructive pulmonary disease exacerbation as assessed by micro-computed tomography.
Kobayashi S, Fujinawa R, Ota F, Kobayashi S, Angata T, Ueno M, Maeno T, Kitazume S, Yoshida K, Ishii T, Gao C, Ohtsubo K, Yamaguchi Y, Betsuyaku T, Kida K, Taniguchi N. Kobayashi S, et al. Among authors: ohtsubo k. Am J Respir Cell Mol Biol. 2013 Dec;49(6):971-7. doi: 10.1165/rcmb.2013-0074OC. Am J Respir Cell Mol Biol. 2013. PMID: 23822858
294 results