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165 results

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R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Holland SJ, Pan A, Franci C, Hu Y, Chang B, Li W, Duan M, Torneros A, Yu J, Heckrodt TJ, Zhang J, Ding P, Apatira A, Chua J, Brandt R, Pine P, Goff D, Singh R, Payan DG, Hitoshi Y. Holland SJ, et al. Among authors: franci c. Cancer Res. 2010 Feb 15;70(4):1544-54. doi: 10.1158/0008-5472.CAN-09-2997. Epub 2010 Feb 9. Cancer Res. 2010. PMID: 20145120
Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth.
Jenkins Y, Markovtsov V, Lang W, Sharma P, Pearsall D, Warner J, Franci C, Huang B, Huang J, Yam GC, Vistan JP, Pali E, Vialard J, Janicot M, Lorens JB, Payan DG, Hitoshi Y. Jenkins Y, et al. Among authors: franci c. Mol Biol Cell. 2005 Dec;16(12):5621-9. doi: 10.1091/mbc.e05-03-0194. Epub 2005 Sep 29. Mol Biol Cell. 2005. PMID: 16195352 Free PMC article.
Multiple roles for the receptor tyrosine kinase axl in tumor formation.
Holland SJ, Powell MJ, Franci C, Chan EW, Friera AM, Atchison RE, McLaughlin J, Swift SE, Pali ES, Yam G, Wong S, Lasaga J, Shen MR, Yu S, Xu W, Hitoshi Y, Bogenberger J, Nör JE, Payan DG, Lorens JB. Holland SJ, et al. Among authors: franci c. Cancer Res. 2005 Oct 15;65(20):9294-303. doi: 10.1158/0008-5472.CAN-05-0993. Cancer Res. 2005. PMID: 16230391
Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells.
Katakam AK, Brightbill H, Franci C, Kung C, Nunez V, Jones C 3rd, Peng I, Jeet S, Wu LC, Mellman I, Delamarre L, Austin CD. Katakam AK, et al. Among authors: franci c. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14664-9. doi: 10.1073/pnas.1520627112. Epub 2015 Nov 11. Proc Natl Acad Sci U S A. 2015. PMID: 26561586 Free PMC article.
Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen.
McLaughlin J, Markovtsov V, Li H, Wong S, Gelman M, Zhu Y, Franci C, Lang D, Pali E, Lasaga J, Low C, Zhao F, Chang B, Gururaja TL, Xu W, Baluom M, Sweeny D, Carroll D, Sran A, Thota S, Parmer M, Romane A, Clemens G, Grossbard E, Qu K, Jenkins Y, Kinoshita T, Taylor V, Holland SJ, Argade A, Singh R, Pine P, Payan DG, Hitoshi Y. McLaughlin J, et al. Among authors: franci c. J Cancer Res Clin Oncol. 2010 Jan;136(1):99-113. doi: 10.1007/s00432-009-0641-1. J Cancer Res Clin Oncol. 2010. PMID: 19609559
165 results