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ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response.
Heijmans J, van Lidth de Jeude JF, Koo BK, Rosekrans SL, Wielenga MC, van de Wetering M, Ferrante M, Lee AS, Onderwater JJ, Paton JC, Paton AW, Mommaas AM, Kodach LL, Hardwick JC, Hommes DW, Clevers H, Muncan V, van den Brink GR. Heijmans J, et al. Among authors: koo bk. Cell Rep. 2013 Apr 25;3(4):1128-39. doi: 10.1016/j.celrep.2013.02.031. Epub 2013 Mar 28. Cell Rep. 2013. PMID: 23545496 Free article.
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
de Lau W, Barker N, Low TY, Koo BK, Li VS, Teunissen H, Kujala P, Haegebarth A, Peters PJ, van de Wetering M, Stange DE, van Es JE, Guardavaccaro D, Schasfoort RB, Mohri Y, Nishimori K, Mohammed S, Heck AJ, Clevers H. de Lau W, et al. Among authors: koo bk. Nature. 2011 Jul 4;476(7360):293-7. doi: 10.1038/nature10337. Nature. 2011. PMID: 21727895
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.
Muñoz J, Stange DE, Schepers AG, van de Wetering M, Koo BK, Itzkovitz S, Volckmann R, Kung KS, Koster J, Radulescu S, Myant K, Versteeg R, Sansom OJ, van Es JH, Barker N, van Oudenaarden A, Mohammed S, Heck AJ, Clevers H. Muñoz J, et al. Among authors: koo bk. EMBO J. 2012 Jun 12;31(14):3079-91. doi: 10.1038/emboj.2012.166. EMBO J. 2012. PMID: 22692129 Free PMC article.
Generation of BAC transgenic epithelial organoids.
Schwank G, Andersson-Rolf A, Koo BK, Sasaki N, Clevers H. Schwank G, et al. Among authors: koo bk. PLoS One. 2013 Oct 18;8(10):e76871. doi: 10.1371/journal.pone.0076871. eCollection 2013. PLoS One. 2013. PMID: 24204693 Free PMC article.
946 results