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Page 1
Bioequivalence of saxagliptin/metformin immediate release (IR) fixed-dose combination tablets and single-component saxagliptin and metformin IR tablets in healthy adult subjects.
Upreti VV, Keung CF, Boulton DW, Chang M, Li L, Tang A, Hsiang BC, Quamina-Edghill D, Frevert EU, Lacreta FP. Upreti VV, et al. Among authors: frevert eu. Clin Drug Investig. 2013 May;33(5):365-74. doi: 10.1007/s40261-013-0075-z. Clin Drug Investig. 2013. PMID: 23549864 Clinical Trial.
The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.
Xu X, Weitzberg M, Keyes RF, Li Q, Wang R, Wang X, Zhang X, Frevert EU, Camp HS, Beutel BA, Sham HL, Gu YG. Xu X, et al. Among authors: frevert eu. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1803-7. doi: 10.1016/j.bmcl.2006.12.047. Epub 2006 Dec 21. Bioorg Med Chem Lett. 2007. PMID: 17234407
Discovery and metabolic stabilization of potent and selective 2-amino-N-(adamant-2-yl) acetamide 11beta-hydroxysteroid dehydrogenase type 1 inhibitors.
Rohde JJ, Pliushchev MA, Sorensen BK, Wodka D, Shuai Q, Wang J, Fung S, Monzon KM, Chiou WJ, Pan L, Deng X, Chovan LE, Ramaiya A, Mullally M, Henry RF, Stolarik DF, Imade HM, Marsh KC, Beno DW, Fey TA, Droz BA, Brune ME, Camp HS, Sham HL, Frevert EU, Jacobson PB, Link JT. Rohde JJ, et al. Among authors: frevert eu. J Med Chem. 2007 Jan 11;50(1):149-64. doi: 10.1021/jm0609364. J Med Chem. 2007. PMID: 17201418
Adamantane sulfone and sulfonamide 11-beta-HSD1 Inhibitors.
Sorensen B, Winn M, Rohde J, Shuai Q, Wang J, Fung S, Monzon K, Chiou W, Stolarik D, Imade H, Pan L, Deng X, Chovan L, Longenecker K, Judge R, Qin W, Brune M, Camp H, Frevert EU, Jacobson P, Link JT. Sorensen B, et al. Among authors: frevert eu. Bioorg Med Chem Lett. 2007 Jan 15;17(2):527-32. doi: 10.1016/j.bmcl.2006.10.008. Epub 2006 Oct 7. Bioorg Med Chem Lett. 2007. PMID: 17070044
Structure-activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity.
Clark RF, Zhang T, Xin Z, Liu G, Wang Y, Hansen TM, Wang X, Wang R, Zhang X, Frevert EU, Camp HS, Beutel BA, Sham HL, Gu YG. Clark RF, et al. Among authors: frevert eu. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6078-81. doi: 10.1016/j.bmcl.2006.08.100. Epub 2006 Sep 14. Bioorg Med Chem Lett. 2006. PMID: 16973360
Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors.
Gu YG, Weitzberg M, Clark RF, Xu X, Li Q, Zhang T, Hansen TM, Liu G, Xin Z, Wang X, Wang R, McNally T, Zinker BA, Frevert EU, Camp HS, Beutel BA, Sham HL. Gu YG, et al. Among authors: frevert eu. J Med Chem. 2006 Jun 29;49(13):3770-3. doi: 10.1021/jm060484v. J Med Chem. 2006. PMID: 16789734
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