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Page 1
Selection of a novel anti-nicotine vaccine: influence of antigen design on antibody function in mice.
Pryde DC, Jones LH, Gervais DP, Stead DR, Blakemore DC, Selby MD, Brown AD, Coe JW, Badland M, Beal DM, Glen R, Wharton Y, Miller GJ, White P, Zhang N, Benoit M, Robertson K, Merson JR, Davis HL, McCluskie MJ. Pryde DC, et al. Among authors: stead dr. PLoS One. 2013 Oct 1;8(10):e76557. doi: 10.1371/journal.pone.0076557. eCollection 2013. PLoS One. 2013. PMID: 24098532 Free PMC article.
Molecular attributes of conjugate antigen influence function of antibodies induced by anti-nicotine vaccine in mice and non-human primates.
McCluskie MJ, Thorn J, Mehelic PR, Kolhe P, Bhattacharya K, Finneman JI, Stead DR, Piatchek MB, Zhang N, Chikh G, Cartier J, Evans DM, Merson JR, Davis HL. McCluskie MJ, et al. Among authors: stead dr. Int Immunopharmacol. 2015 Apr;25(2):518-27. doi: 10.1016/j.intimp.2015.02.030. Epub 2015 Feb 28. Int Immunopharmacol. 2015. PMID: 25737198
Anti-nicotine vaccines: Comparison of adjuvanted CRM197 and Qb-VLP conjugate formulations for immunogenicity and function in non-human primates.
McCluskie MJ, Thorn J, Gervais DP, Stead DR, Zhang N, Benoit M, Cartier J, Kim IJ, Bhattacharya K, Finneman JI, Merson JR, Davis HL. McCluskie MJ, et al. Among authors: stead dr. Int Immunopharmacol. 2015 Dec;29(2):663-671. doi: 10.1016/j.intimp.2015.09.012. Epub 2015 Sep 26. Int Immunopharmacol. 2015. PMID: 26404190
The effect of preexisting anti-carrier immunity on subsequent responses to CRM197 or Qb-VLP conjugate vaccines.
McCluskie MJ, Evans DM, Zhang N, Benoit M, McElhiney SP, Unnithan M, DeMarco SC, Clay B, Huber C, Deora A, Thorn JM, Stead DR, Merson JR, Davis HL. McCluskie MJ, et al. Among authors: stead dr. Immunopharmacol Immunotoxicol. 2016 Jun;38(3):184-96. doi: 10.3109/08923973.2016.1165246. Epub 2016 Apr 27. Immunopharmacol Immunotoxicol. 2016. PMID: 27121368
Effects of Conformational Changes in Peptide-CRM197 Conjugate Vaccines.
Jaffe J, Wucherer K, Sperry J, Zou Q, Chang Q, Massa MA, Bhattacharya K, Kumar S, Caparon M, Stead D, Wright P, Dirksen A, Francis MB. Jaffe J, et al. Bioconjug Chem. 2019 Jan 16;30(1):47-53. doi: 10.1021/acs.bioconjchem.8b00661. Epub 2018 Dec 12. Bioconjug Chem. 2019. PMID: 30475601