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Page 1
(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.
dos Santos GA, Abreu e Lima RS, Pestana CR, Lima AS, Scheucher PS, Thomé CH, Gimenes-Teixeira HL, Santana-Lemos BA, Lucena-Araujo AR, Rodrigues FP, Nasr R, Uyemura SA, Falcão RP, de Thé H, Pandolfi PP, Curti C, Rego EM. dos Santos GA, et al. Among authors: gimenes teixeira hl. Leukemia. 2012 Mar;26(3):451-60. doi: 10.1038/leu.2011.216. Epub 2011 Aug 26. Leukemia. 2012. PMID: 21869839
Apoptosis induction by (+)alpha-tocopheryl succinate in the absence or presence of all-trans retinoic acid and arsenic trioxide in NB4, NB4-R2 and primary APL cells.
Freitas RA, Silva dos Santos GA, Gimenes Teixeira HL, Scheucher PS, Lucena-Araujo AR, Lima AS, Abreu e Lima RS, Garcia AB, Jordão AA Jr, Falcão RP, Vannucchi H, Rego EM. Freitas RA, et al. Among authors: gimenes teixeira hl. Leuk Res. 2009 Jul;33(7):958-63. doi: 10.1016/j.leukres.2008.09.035. Epub 2008 Nov 14. Leuk Res. 2009. PMID: 19013639
Interaction of 10-(octyloxy) decyl-2-(trimethylammonium) ethyl phosphate with mimetic membranes and cytotoxic effect on leukemic cells.
dos Santos GA, Thomé CH, Ferreira GA, Yoneda JS, Nobre TM, Daghastanli KR, Scheucher PS, Gimenes-Teixeira HL, Constantino MG, de Oliveira KT, Faça VM, Falcão RP, Greene LJ, Rego EM, Ciancaglini P. dos Santos GA, et al. Among authors: gimenes teixeira hl. Biochim Biophys Acta. 2010 Sep;1798(9):1714-23. doi: 10.1016/j.bbamem.2010.05.013. Epub 2010 May 19. Biochim Biophys Acta. 2010. PMID: 20488162 Free article.