Akahata W - Search Results

1

Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization.

Sun S, Xiang Y, Akahata W, Holdaway H, Pal P, Zhang X, Diamond MS, Nabel GJ, Rossmann MG. Sun S, et al. Among authors: akahata w. Elife. 2013 Apr 2;2:e00435. doi: 10.7554/eLife.00435. Elife. 2013. PMID: 23577234 Free PMC article.

2

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus.

Pal P, Dowd KA, Brien JD, Edeling MA, Gorlatov S, Johnson S, Lee I, Akahata W, Nabel GJ, Richter MK, Smit JM, Fremont DH, Pierson TC, Heise MT, Diamond MS. Pal P, et al. Among authors: akahata w. PLoS Pathog. 2013;9(4):e1003312. doi: 10.1371/journal.ppat.1003312. Epub 2013 Apr 18. PLoS Pathog. 2013. PMID: 23637602 Free PMC article.

3

Cryo-EM structures elucidate neutralizing mechanisms of anti-chikungunya human monoclonal antibodies with therapeutic activity.

Long F, Fong RH, Austin SK, Chen Z, Klose T, Fokine A, Liu Y, Porta J, Sapparapu G, Akahata W, Doranz BJ, Crowe JE Jr, Diamond MS, Rossmann MG. Long F, et al. Among authors: akahata w. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13898-903. doi: 10.1073/pnas.1515558112. Epub 2015 Oct 26. Proc Natl Acad Sci U S A. 2015. PMID: 26504196 Free PMC article.

4

Structural Studies of Chikungunya Virus-Like Particles Complexed with Human Antibodies: Neutralization and Cell-to-Cell Transmission.

Porta J, Mangala Prasad V, Wang CI, Akahata W, Ng LF, Rossmann MG. Porta J, et al. Among authors: akahata w. J Virol. 2015 Nov 4;90(3):1169-77. doi: 10.1128/JVI.02364-15. Print 2016 Feb 1. J Virol. 2015. PMID: 26537684 Free PMC article.

5

Structural studies of Chikungunya virus maturation.

Yap ML, Klose T, Urakami A, Hasan SS, Akahata W, Rossmann MG. Yap ML, et al. Among authors: akahata w. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13703-13707. doi: 10.1073/pnas.1713166114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203665 Free PMC article.

6

A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection.

Akahata W, Yang ZY, Andersen H, Sun S, Holdaway HA, Kong WP, Lewis MG, Higgs S, Rossmann MG, Rao S, Nabel GJ. Akahata W, et al. Nat Med. 2010 Mar;16(3):334-8. doi: 10.1038/nm.2105. Epub 2010 Jan 28. Nat Med. 2010. PMID: 20111039 Free PMC article.

7

A specific domain of the Chikungunya virus E2 protein regulates particle formation in human cells: implications for alphavirus vaccine design.

Akahata W, Nabel GJ. Akahata W, et al. J Virol. 2012 Aug;86(16):8879-83. doi: 10.1128/JVI.00370-12. Epub 2012 May 30. J Virol. 2012. PMID: 22647698 Free PMC article.

8

Development of a Novel Virus-Like Particle Vaccine Platform That Mimics the Immature Form of Alphavirus.

Urakami A, Sakurai A, Ishikawa M, Yap ML, Flores-Garcia Y, Haseda Y, Aoshi T, Zavala FP, Rossmann MG, Kuno S, Ueno R, Akahata W. Urakami A, et al. Among authors: akahata w. Clin Vaccine Immunol. 2017 Jul 5;24(7):e00090-17. doi: 10.1128/CVI.00090-17. Print 2017 Jul. Clin Vaccine Immunol. 2017. PMID: 28515133 Free PMC article.

9

Comparative immunogenicity of human immunodeficiency virus particles and corresponding polypeptides in a DNA vaccine.

Akahata W, Yang ZY, Nabel GJ. Akahata W, et al. J Virol. 2005 Jan;79(1):626-31. doi: 10.1128/JVI.79.1.626-631.2005. J Virol. 2005. PMID: 15596858 Free PMC article.

10

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates.

Ko SY, Akahata W, Yang ES, Kong WP, Burke CW, Honnold SP, Nichols DK, Huang YS, Schieber GL, Carlton K, DaSilva L, Traina-Dorge V, Vanlandingham DL, Tsybovsky Y, Stephens T, Baxa U, Higgs S, Roy CJ, Glass PJ, Mascola JR, Nabel GJ, Rao SS. Ko SY, et al. Among authors: akahata w. Sci Transl Med. 2019 May 15;11(492):eaav3113. doi: 10.1126/scitranslmed.aav3113. Sci Transl Med. 2019. PMID: 31092692

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