Gordon VL - Search Results

1

Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms.

Axelrod M, Gordon VL, Conaway M, Tarcsafalvi A, Neitzke DJ, Gioeli D, Weber MJ. Axelrod M, et al. Among authors: gordon vl. Oncotarget. 2013 Apr;4(4):622-35. doi: 10.18632/oncotarget.938. Oncotarget. 2013. PMID: 23599172 Free PMC article.

2

Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization.

Gioeli D, Black BE, Gordon V, Spencer A, Kesler CT, Eblen ST, Paschal BM, Weber MJ. Gioeli D, et al. Mol Endocrinol. 2006 Mar;20(3):503-15. doi: 10.1210/me.2005-0351. Epub 2005 Nov 10. Mol Endocrinol. 2006. PMID: 16282370

3

Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor.

Kraus S, Gioeli D, Vomastek T, Gordon V, Weber MJ. Kraus S, et al. Cancer Res. 2006 Nov 15;66(22):11047-54. doi: 10.1158/0008-5472.CAN-06-0596. Cancer Res. 2006. PMID: 17108144

4

CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation.

Gordon V, Bhadel S, Wunderlich W, Zhang J, Ficarro SB, Mollah SA, Shabanowitz J, Hunt DF, Xenarios I, Hahn WC, Conaway M, Carey MF, Gioeli D. Gordon V, et al. Mol Endocrinol. 2010 Dec;24(12):2267-80. doi: 10.1210/me.2010-0238. Epub 2010 Oct 27. Mol Endocrinol. 2010. PMID: 20980437 Free PMC article.

5

Combinatorial drug screening identifies synergistic co-targeting of Bruton's tyrosine kinase and the proteasome in mantle cell lymphoma.

Axelrod M, Ou Z, Brett LK, Zhang L, Lopez ER, Tamayo AT, Gordon V, Ford RJ, Williams ME, Pham LV, Weber MJ, Wang ML. Axelrod M, et al. Leukemia. 2014 Feb;28(2):407-10. doi: 10.1038/leu.2013.249. Epub 2013 Aug 27. Leukemia. 2014. PMID: 23979520 Free PMC article. No abstract available.

6

p70S6 kinase is a critical node that integrates HER-family and PI3 kinase signaling networks.

Axelrod MJ, Gordon V, Mendez RE, Leimgruber SS, Conaway MR, Sharlow ER, Jameson MJ, Gioeli DG, Weber MJ. Axelrod MJ, et al. Cell Signal. 2014 Aug;26(8):1627-35. doi: 10.1016/j.cellsig.2014.03.013. Epub 2014 Mar 21. Cell Signal. 2014. PMID: 24662264 Free PMC article.

7

Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL.

Jayappa KD, Portell CA, Gordon VL, Capaldo BJ, Bekiranov S, Axelrod MJ, Brett LK, Wulfkuhle JD, Gallagher RI, Petricoin EF, Bender TP, Williams ME, Weber MJ. Jayappa KD, et al. Among authors: gordon vl. Blood Adv. 2017 Jun 13;1(14):933-946. doi: 10.1182/bloodadvances.2016004176. Blood Adv. 2017. PMID: 29034364 Free PMC article.

8

Extrinsic interactions in the microenvironment in vivo activate an antiapoptotic multidrug-resistant phenotype in CLL.

Jayappa KD, Gordon VL, Morris CG, Wilson B, Shetty BD, Cios KJ, Arora PC, Isaac KM, Saha S, Bender TP, Williams ME, Portell CA, Weber MJ. Jayappa KD, et al. Among authors: gordon vl. Blood Adv. 2021 Sep 14;5(17):3497-3510. doi: 10.1182/bloodadvances.2020003944. Blood Adv. 2021. PMID: 34432864 Free PMC article.

9

PP2A modulation overcomes multidrug resistance in chronic lymphocytic leukemia via mPTP-dependent apoptosis.

Jayappa KD, Tran B, Gordon VL, Morris C, Saha S, Farrington CC, O'Connor CM, Zawacki KP, Isaac KM, Kester M, Bender TP, Williams ME, Portell CA, Weber MJ, Narla G. Jayappa KD, et al. Among authors: gordon vl. J Clin Invest. 2023 Jul 3;133(13):e155938. doi: 10.1172/JCI155938. J Clin Invest. 2023. PMID: 37166997 Free PMC article.

10

Inhibition of insulin receptor phosphorylation by indomethacin.

Malchoff CD, Messina JL, Gordon V, Tamura S, Larner J. Malchoff CD, et al. Mol Cell Biochem. 1985 Nov;69(1):83-91. doi: 10.1007/BF00225930. Mol Cell Biochem. 1985. PMID: 3935910

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