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Mutations in LRRC50 predispose zebrafish and humans to seminomas.
Basten SG, Davis EE, Gillis AJ, van Rooijen E, Stoop H, Babala N, Logister I, Heath ZG, Jonges TN, Katsanis N, Voest EE, van Eeden FJ, Medema RH, Ketting RF, Schulte-Merker S, Looijenga LH, Giles RH. Basten SG, et al. Among authors: medema rh. PLoS Genet. 2013 Apr;9(4):e1003384. doi: 10.1371/journal.pgen.1003384. Epub 2013 Apr 11. PLoS Genet. 2013. PMID: 23599692 Free PMC article.
Liver surgery induces an immediate mobilization of progenitor cells in liver cancer patients: A potential role for G-CSF.
Langenberg MH, Nijkamp MW, Roodhart JM, Snoeren N, Tang T, Shaked Y, van Hillegersberg R, Witteveen PO, Vermaat JS, Kranenburg O, Kerbel RS, Medema RH, Borel Rinkes IH, Voest EE. Langenberg MH, et al. Among authors: medema rh. Cancer Biol Ther. 2010 May 1;9(9):743-8. doi: 10.4161/cbt.9.9.11551. Epub 2010 May 18. Cancer Biol Ther. 2010. PMID: 20215863 Free article.
Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids.
Roodhart JM, Daenen LG, Stigter EC, Prins HJ, Gerrits J, Houthuijzen JM, Gerritsen MG, Schipper HS, Backer MJ, van Amersfoort M, Vermaat JS, Moerer P, Ishihara K, Kalkhoven E, Beijnen JH, Derksen PW, Medema RH, Martens AC, Brenkman AB, Voest EE. Roodhart JM, et al. Among authors: medema rh. Cancer Cell. 2011 Sep 13;20(3):370-83. doi: 10.1016/j.ccr.2011.08.010. Cancer Cell. 2011. PMID: 21907927 Free article.
Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint.
Kleiblova P, Shaltiel IA, Benada J, Ševčík J, Pecháčková S, Pohlreich P, Voest EE, Dundr P, Bartek J, Kleibl Z, Medema RH, Macurek L. Kleiblova P, et al. Among authors: medema rh. J Cell Biol. 2013 May 13;201(4):511-21. doi: 10.1083/jcb.201210031. Epub 2013 May 6. J Cell Biol. 2013. PMID: 23649806 Free PMC article.
Taxanes trigger cancer cell killing in vivo by inducing non-canonical T cell cytotoxicity.
Vennin C, Cattaneo CM, Bosch L, Vegna S, Ma X, Damstra HGJ, Martinovic M, Tsouri E, Ilic M, Azarang L, van Weering JRT, Pulver E, Zeeman AL, Schelfhorst T, Lohuis JO, Rios AC, Dekkers JF, Akkari L, Menezes R, Medema R, Baglio SR, Akhmanova A, Linn SC, Lemeer S, Pegtel DM, Voest EE, van Rheenen J. Vennin C, et al. Cancer Cell. 2023 Jun 12;41(6):1170-1185.e12. doi: 10.1016/j.ccell.2023.05.009. Cancer Cell. 2023. PMID: 37311414 Free article.
252 results