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Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure.
Takemoto K, Hatano E, Iwaisako K, Takeiri M, Noma N, Ohmae S, Toriguchi K, Tanabe K, Tanaka H, Seo S, Taura K, Machida K, Takeda N, Saji S, Uemoto S, Asagiri M. Takemoto K, et al. Among authors: takeiri m. FEBS Open Bio. 2014 Sep 6;4:777-87. doi: 10.1016/j.fob.2014.08.007. eCollection 2014. FEBS Open Bio. 2014. PMID: 25349782 Free PMC article.
Necrostatin-7 suppresses RANK-NFATc1 signaling and attenuates macrophage to osteoclast differentiation.
Fuji H, Ohmae S, Noma N, Takeiri M, Yasutomi H, Izumi K, Ito M, Toyomoto M, Iwaki S, Takemoto K, Seo S, Taura K, Hida S, Aoyama M, Ishihama Y, Hagiwara M, Takeda N, Hatano E, Iwaisako K, Uemoto S, Asagiri M. Fuji H, et al. Among authors: takeiri m. Biochem Biophys Res Commun. 2018 Sep 5;503(2):544-549. doi: 10.1016/j.bbrc.2018.05.153. Epub 2018 Jul 7. Biochem Biophys Res Commun. 2018. PMID: 29800570
A new NF-κB inhibitor based on the amino-epoxyquinol core of DHMEQ.
Saitoh T, Shimada C, Takeiri M, Shiino M, Ohba S, Obata R, Ishikawa Y, Umezawa K, Nishiyama S. Saitoh T, et al. Among authors: takeiri m. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5638-42. doi: 10.1016/j.bmcl.2010.08.036. Epub 2010 Aug 11. Bioorg Med Chem Lett. 2010. PMID: 20801656
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