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A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins.
Keysar SB, Astling DP, Anderson RT, Vogler BW, Bowles DW, Morton JJ, Paylor JJ, Glogowska MJ, Le PN, Eagles-Soukup JR, Kako SL, Takimoto SM, Sehrt DB, Umpierrez A, Pittman MA, Macfadden SM, Helber RM, Peterson S, Hausman DF, Said S, Leem TH, Goddard JA, Arcaroli JJ, Messersmith WA, Robinson WA, Hirsch FR, Varella-Garcia M, Raben D, Wang XJ, Song JI, Tan AC, Jimeno A. Keysar SB, et al. Among authors: umpierrez a. Mol Oncol. 2013 Aug;7(4):776-90. doi: 10.1016/j.molonc.2013.03.004. Epub 2013 Apr 4. Mol Oncol. 2013. PMID: 23607916 Free PMC article.
The dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas.
Anderson RT, Keysar SB, Bowles DW, Glogowska MJ, Astling DP, Morton JJ, Le P, Umpierrez A, Eagles-Soukup J, Gan GN, Vogler BW, Sehrt D, Takimoto SM, Aisner DL, Wilhelm F, Frederick BA, Varella-Garcia M, Tan AC, Jimeno A. Anderson RT, et al. Among authors: umpierrez a. Mol Cancer Ther. 2013 Oct;12(10):1994-2005. doi: 10.1158/1535-7163.MCT-13-0206. Epub 2013 Jul 19. Mol Cancer Ther. 2013. PMID: 23873848 Free PMC article.
Loss of humoral response 3 months after SARS-CoV-2 vaccination in the CKD spectrum: the multicentric SENCOVAC study.
Quiroga B, Soler MJ, Ortiz A, Bernat A, Muñoz Díaz AB, Jarava Mantecón CJ, Gómez Pérez VO, Calderón González C, Cervienka M, Mazuecos A, Cazorla JM, Carnerero Di Riso M, Martínez S, Ortega Diaz M, Lucena Valverde R, Sánchez Márquez MG, Lancho Novillo C, González Parra E, Gracia-Iguacel C, Rodrigo De Tomas MT, Aguilar Cervera MC, Giorgi M, Muñoz Ramos P, Macías Carmona N, Toapanta N, Cigarrán S, Ruiz San Millán JC, Santana Estupiñán R, Crespo M, Villacorta Linaza B, Jimeno Martín MI, Rodríguez-Osorio Jiménez L, Soriano S, González Ferri D, Pizarro Sánchez MS, Yugueros A, Leyva A, Rojas J, Gansevoort RT, de Sequera P; SENCOVAC collaborative network. Quiroga B, et al. Nephrol Dial Transplant. 2022 Apr 25;37(5):994-999. doi: 10.1093/ndt/gfac007. Nephrol Dial Transplant. 2022. PMID: 35022757 Free PMC article. No abstract available.
Safety and immediate humoral response of COVID-19 vaccines in chronic kidney disease patients: the SENCOVAC study.
Quiroga B, Soler MJ, Ortiz A, Martínez Vaquera S, Jarava Mantecón CJ, Useche G, Sánchez Márquez MG, Carnerero M, Jaldo Rodríguez MT, Muñoz Ramos P, Ruiz San Millán JC, Toapanta N, Gracia-Iguacel C, Aguilar Cervera MC, Balibrea Lara N, Leyva A, Rojas J, Gansevoort RT, de Sequera P; SENCOVAC Collaborative Network. Quiroga B, et al. Nephrol Dial Transplant. 2022 Sep 22;37(10):1868-1878. doi: 10.1093/ndt/gfab313. Nephrol Dial Transplant. 2022. PMID: 34788858 Free PMC article.
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