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Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity.
Liang P, Lan F, Lee AS, Gong T, Sanchez-Freire V, Wang Y, Diecke S, Sallam K, Knowles JW, Wang PJ, Nguyen PK, Bers DM, Robbins RC, Wu JC. Liang P, et al. Among authors: diecke s. Circulation. 2013 Apr 23;127(16):1677-91. doi: 10.1161/CIRCULATIONAHA.113.001883. Epub 2013 Mar 21. Circulation. 2013. PMID: 23519760 Free PMC article.
Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation.
Huber BC, Ransohoff JD, Ransohoff KJ, Riegler J, Ebert A, Kodo K, Gong Y, Sanchez-Freire V, Dey D, Kooreman NG, Diecke S, Zhang WY, Odegaard J, Hu S, Gold JD, Robbins RC, Wu JC. Huber BC, et al. Among authors: diecke s. Stem Cells. 2013 Nov;31(11):2354-63. doi: 10.1002/stem.1501. Stem Cells. 2013. PMID: 24038578 Free PMC article.
Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.
de Almeida PE, Meyer EH, Kooreman NG, Diecke S, Dey D, Sanchez-Freire V, Hu S, Ebert A, Odegaard J, Mordwinkin NM, Brouwer TP, Lo D, Montoro DT, Longaker MT, Negrin RS, Wu JC. de Almeida PE, et al. Among authors: diecke s. Nat Commun. 2014 May 30;5:3903. doi: 10.1038/ncomms4903. Nat Commun. 2014. PMID: 24875164 Free PMC article.
Chemically defined generation of human cardiomyocytes.
Burridge PW, Matsa E, Shukla P, Lin ZC, Churko JM, Ebert AD, Lan F, Diecke S, Huber B, Mordwinkin NM, Plews JR, Abilez OJ, Cui B, Gold JD, Wu JC. Burridge PW, et al. Among authors: diecke s. Nat Methods. 2014 Aug;11(8):855-60. doi: 10.1038/nmeth.2999. Epub 2014 Jun 15. Nat Methods. 2014. PMID: 24930130 Free PMC article.
Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform.
Sharma A, Marceau C, Hamaguchi R, Burridge PW, Rajarajan K, Churko JM, Wu H, Sallam KI, Matsa E, Sturzu AC, Che Y, Ebert A, Diecke S, Liang P, Red-Horse K, Carette JE, Wu SM, Wu JC. Sharma A, et al. Among authors: diecke s. Circ Res. 2014 Aug 29;115(6):556-66. doi: 10.1161/CIRCRESAHA.115.303810. Epub 2014 Jul 11. Circ Res. 2014. PMID: 25015077 Free PMC article.
Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system.
Ebert AD, Kodo K, Liang P, Wu H, Huber BC, Riegler J, Churko J, Lee J, de Almeida P, Lan F, Diecke S, Burridge PW, Gold JD, Mochly-Rosen D, Wu JC. Ebert AD, et al. Among authors: diecke s. Sci Transl Med. 2014 Sep 24;6(255):255ra130. doi: 10.1126/scitranslmed.3009027. Sci Transl Med. 2014. PMID: 25253673 Free PMC article.
84 results