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The High Mobility Group A1 (HMGA1) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 (MMP-2) in a subset of tumors.
Hillion J, Roy S, Heydarian M, Cope L, Xian L, Koo M, Luo LZ, Kellyn K, Ronnett BM, Huso T, Armstrong D, Reddy K, Huso DL, Resar LMS. Hillion J, et al. Among authors: roy s. Gynecol Oncol. 2016 Jun;141(3):580-587. doi: 10.1016/j.ygyno.2016.03.020. Epub 2016 Apr 8. Gynecol Oncol. 2016. PMID: 27001612 Free PMC article.
Downregulation of 5-hydroxymethylcytosine is an early event in pancreatic tumorigenesis.
Fujikura K, Alruwaii ZI, Haffner MC, Trujillo MA, Roberts NJ, Hong SM, Macgregor-Das A, Goggins MG, Roy S, Meeker AK, Ding D, Wright M, He J, Hruban RH, Wood LD. Fujikura K, et al. Among authors: roy s. J Pathol. 2021 Jul;254(3):279-288. doi: 10.1002/path.5682. Epub 2021 May 21. J Pathol. 2021. PMID: 33870509 Free PMC article.
Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.
Mukhopadhyay R, Roy S, Venkatadri R, Su YP, Ye W, Barnaeva E, Mathews Griner L, Southall N, Hu X, Wang AQ, Xu X, Dulcey AE, Marugan JJ, Ferrer M, Arav-Boger R. Mukhopadhyay R, et al. Among authors: roy s. PLoS Pathog. 2016 Jun 23;12(6):e1005717. doi: 10.1371/journal.ppat.1005717. eCollection 2016 Jun. PLoS Pathog. 2016. PMID: 27336364 Free PMC article.
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