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Functional genomics identifies five distinct molecular subtypes with clinical relevance and pathways for growth control in epithelial ovarian cancer.
Tan TZ, Miow QH, Huang RY, Wong MK, Ye J, Lau JA, Wu MC, Bin Abdul Hadi LH, Soong R, Choolani M, Davidson B, Nesland JM, Wang LZ, Matsumura N, Mandai M, Konishi I, Goh BC, Chang JT, Thiery JP, Mori S. Tan TZ, et al. Among authors: lau ja. EMBO Mol Med. 2013 Jul;5(7):1051-66. doi: 10.1002/emmm.201201823. Epub 2013 May 13. EMBO Mol Med. 2013. PMID: 23666744 Free PMC article.
Utilization of the Eμ-Myc mouse to model heterogeneity of therapeutic response.
Rempel RE, Jiang X, Fullerton P, Tan TZ, Ye J, Lau JA, Mori S, Chi JT, Nevins JR, Friedman DR. Rempel RE, et al. Among authors: lau ja. Mol Cancer Ther. 2014 Dec;13(12):3219-29. doi: 10.1158/1535-7163.MCT-13-0044. Epub 2014 Oct 27. Mol Cancer Ther. 2014. PMID: 25349303 Free PMC article.
Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation.
Kong LR, Ong RW, Tan TZ, Mohamed Salleh NAB, Thangavelu M, Chan JV, Koh LYJ, Periyasamy G, Lau JA, Le TBU, Wang L, Lee M, Kannan S, Verma CS, Lim CM, Chng WJ, Lane DP, Venkitaraman A, Hung HT, Cheok CF, Goh BC. Kong LR, et al. Among authors: lau ja. Nat Commun. 2020 Apr 29;11(1):2086. doi: 10.1038/s41467-020-15608-y. Nat Commun. 2020. PMID: 32350249 Free PMC article.
Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia.
Ong KOK, Mok MMH, Niibori-Nambu A, Du L, Yanagida M, Wang CQ, Bahirvani AG, Chin DWL, Koh CP, Ng KP, Yamashita N, Jacob B, Yokomizo T, Takizawa H, Matsumura T, Suda T, Lau JA, Tan TZ, Mori S, Yang H, Iwasaki M, Minami T, Asou N, Sun QY, Ding LW, Koeffler HP, Tenen DG, Shimizu R, Yamamoto M, Ito Y, Kham SKY, Yeoh AE, Chng WJ, Osato M. Ong KOK, et al. Among authors: lau ja. Exp Hematol. 2024 Sep;137:104255. doi: 10.1016/j.exphem.2024.104255. Epub 2024 Jun 13. Exp Hematol. 2024. PMID: 38876252
Integration of Antiangiogenic Therapy with Cisplatin and Gemcitabine Chemotherapy in Patients with Nasopharyngeal Carcinoma.
Chong WQ, Lim CM, Sinha AK, Tan CS, Chan GHJ, Huang Y, Kumarakulasinghe NB, Sundar R, Jeyasekharan AD, Loh WS, Tay JK, Yadav K, Wang L, Wong AL, Kong LR, Soo RA, Lau JA, Soon YY, Goh RM, Ho FCH, Chong SM, Lee SC, Loh KS, Tai BC, Lim YC, Goh BC. Chong WQ, et al. Among authors: lau ja. Clin Cancer Res. 2020 Oct 15;26(20):5320-5328. doi: 10.1158/1078-0432.CCR-20-1727. Epub 2020 Aug 14. Clin Cancer Res. 2020. PMID: 32816944 Clinical Trial.
The value of long-term ecological research for evolutionary insights.
Cocciardi JM, Hoffman AM, Alvarado-Serrano DF, Anderson J, Blumstein M, Boehm EL, Bolin LG, Borokini IT, Bradburd GS, Branch HA, Brudvig LA, Chen Y, Collins SL, Des Marais DL, Gamba D, Hanan NP, Howard MM, Jaros J, Juenger TE, Kooyers NJ, Kottler EJ, Lau JA, Menon M, Moeller DA, Mozdzer TJ, Sheth SN, Smith M, Toll K, Ungerer MC, Vahsen ML, Wadgymar SM, Waananen A, Whitney KD, Avolio ML. Cocciardi JM, et al. Among authors: lau ja. Nat Ecol Evol. 2024 Sep;8(9):1584-1592. doi: 10.1038/s41559-024-02464-y. Epub 2024 Aug 2. Nat Ecol Evol. 2024. PMID: 39095611 Review.
78 results