Rose-John S - Search Results

1

Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor.

Floss DM, Mrotzek S, Klöcker T, Schröder J, Grötzinger J, Rose-John S, Scheller J. Floss DM, et al. J Biol Chem. 2013 Jul 5;288(27):19386-400. doi: 10.1074/jbc.M112.432153. Epub 2013 May 14. J Biol Chem. 2013. PMID: 23673666 Free PMC article.

2

Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.

Ehlers M, Grötzinger J, deHon FD, Müllberg J, Brakenhoff JP, Liu J, Wollmer A, Rose-John S. Ehlers M, et al. J Immunol. 1994 Aug 15;153(4):1744-53. J Immunol. 1994. PMID: 7519211

3

Site-directed mutagenesis of human CNTF: functional analysis of recombinant variants.

Thier M, Simon R, Krüttgen A, Rose-John S, Heinrich PC, Schröder JM, Weis J. Thier M, et al. J Neurosci Res. 1995 Apr 15;40(6):826-35. doi: 10.1002/jnr.490400614. J Neurosci Res. 1995. PMID: 7629895

4

Leucine-58 in the putative 5th helical region of human interleukin (IL)-6 is important for activation of the IL-6 signal transducer, gp130.

de Hon FD, Klaasse Bos HK, Ebeling SB, Grötzinger J, Kurapkat G, Rose-John S, Aarden LA, Brakenhoff JP. de Hon FD, et al. FEBS Lett. 1995 Aug 7;369(2-3):187-91. doi: 10.1016/0014-5793(95)00741-q. FEBS Lett. 1995. PMID: 7649255 Free article.

5

The soluble interleukin-6 receptor.

Rose-John S, Ehlers M, Grötzinger J, Müllberg J. Rose-John S, et al. Ann N Y Acad Sci. 1995 Jul 21;762:207-20; discussion 220-1. Ann N Y Acad Sci. 1995. PMID: 7668529 No abstract available.

6

Residues 77-95 of the human interleuken-6 protein are responsible for receptor binding and residues 41-56 for signal transduction.

Ehlers M, Grötzinger J, de Hon FD, Müllberg J, Brakenhoff JP, Wollmer A, Rose-John S. Ehlers M, et al. Ann N Y Acad Sci. 1995 Jul 21;762:400-2. doi: 10.1111/j.1749-6632.1995.tb32347.x. Ann N Y Acad Sci. 1995. PMID: 7668541 No abstract available.

7

Combining two mutations of human interleukin-6 that affect gp130 activation results in a potent interleukin-6 receptor antagonist on human myeloma cells.

Ehlers M, de Hon FD, Bos HK, Horsten U, Kurapkat G, van De Leur HS, Grötzinger J, Wollmer A, Brakenhoff JP, Rose-John S. Ehlers M, et al. J Biol Chem. 1995 Apr 7;270(14):8158-63. doi: 10.1074/jbc.270.14.8158. J Biol Chem. 1995. PMID: 7713920 Free article.

8

Identification of a region within the cytoplasmic domain of the interleukin-6 (IL-6) signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor.

Dittrich E, Rose-John S, Gerhartz C, Müllberg J, Stoyan T, Yasukawa K, Heinrich PC, Graeve L. Dittrich E, et al. J Biol Chem. 1994 Jul 22;269(29):19014-20. J Biol Chem. 1994. PMID: 8034658 Free article.

9

Development of a human interleukin-6 receptor antagonist.

Brakenhoff JP, de Hon FD, Fontaine V, ten Boekel E, Schooltink H, Rose-John S, Heinrich PC, Content J, Aarden LA. Brakenhoff JP, et al. J Biol Chem. 1994 Jan 7;269(1):86-93. J Biol Chem. 1994. PMID: 8276883 Free article.

10

Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding.

van Dam M, Müllberg J, Schooltink H, Stoyan T, Brakenhoff JP, Graeve L, Heinrich PC, Rose-John S. van Dam M, et al. J Biol Chem. 1993 Jul 15;268(20):15285-90. J Biol Chem. 1993. PMID: 8325898 Free article.

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