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The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak.
Cao X, Yap JL, Newell-Rogers MK, Peddaboina C, Jiang W, Papaconstantinou HT, Jupitor D, Rai A, Jung KY, Tubin RP, Yu W, Vanommeslaeghe K, Wilder PT, MacKerell AD Jr, Fletcher S, Smythe RW. Cao X, et al. Mol Cancer. 2013 May 16;12(1):42. doi: 10.1186/1476-4598-12-42. Mol Cancer. 2013. PMID: 23680104 Free PMC article.
Prolonged intake of desloratadine: mesenteric lymphatic vessel dysfunction and development of obesity/metabolic syndrome.
Gasheva OY, Tsoy Nizamutdinova I, Hargrove L, Gobbell C, Troyanova-Wood M, Alpini SF, Pal S, Du C, Hitt AR, Yakovlev VV, Newell-Rogers MK, Zawieja DC, Meininger CJ, Alpini GD, Francis H, Gashev AA. Gasheva OY, et al. Among authors: newell rogers mk. Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1;316(1):G217-G227. doi: 10.1152/ajpgi.00321.2018. Epub 2018 Nov 26. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30475062 Free PMC article.
24 results