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Stages of pTDP-43 pathology in amyotrophic lateral sclerosis.
Brettschneider J, Del Tredici K, Toledo JB, Robinson JL, Irwin DJ, Grossman M, Suh E, Van Deerlin VM, Wood EM, Baek Y, Kwong L, Lee EB, Elman L, McCluskey L, Fang L, Feldengut S, Ludolph AC, Lee VM, Braak H, Trojanowski JQ. Brettschneider J, et al. Among authors: kwong l. Ann Neurol. 2013 Jul;74(1):20-38. doi: 10.1002/ana.23937. Epub 2013 Jun 19. Ann Neurol. 2013. PMID: 23686809 Free PMC article.
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ, Lee VM. Neumann M, et al. Among authors: kwong lk. Science. 2006 Oct 6;314(5796):130-3. doi: 10.1126/science.1134108. Science. 2006. PMID: 17023659
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies.
Uryu K, Nakashima-Yasuda H, Forman MS, Kwong LK, Clark CM, Grossman M, Miller BL, Kretzschmar HA, Lee VM, Trojanowski JQ, Neumann M. Uryu K, et al. Among authors: kwong lk. J Neuropathol Exp Neurol. 2008 Jun;67(6):555-64. doi: 10.1097/NEN.0b013e31817713b5. J Neuropathol Exp Neurol. 2008. PMID: 18520774 Free PMC article.
Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Igaz LM, Kwong LK, Xu Y, Truax AC, Uryu K, Neumann M, Clark CM, Elman LB, Miller BL, Grossman M, McCluskey LF, Trojanowski JQ, Lee VM. Igaz LM, et al. Among authors: kwong lk. Am J Pathol. 2008 Jul;173(1):182-94. doi: 10.2353/ajpath.2008.080003. Epub 2008 Jun 5. Am J Pathol. 2008. PMID: 18535185 Free PMC article.
Clinical and pathological continuum of multisystem TDP-43 proteinopathies.
Geser F, Martinez-Lage M, Robinson J, Uryu K, Neumann M, Brandmeir NJ, Xie SX, Kwong LK, Elman L, McCluskey L, Clark CM, Malunda J, Miller BL, Zimmerman EA, Qian J, Van Deerlin V, Grossman M, Lee VM, Trojanowski JQ. Geser F, et al. Among authors: kwong lk. Arch Neurol. 2009 Feb;66(2):180-9. doi: 10.1001/archneurol.2008.558. Arch Neurol. 2009. PMID: 19204154 Free PMC article.
TDP-43 skeins show properties of amyloid in a subset of ALS cases.
Robinson JL, Geser F, Stieber A, Umoh M, Kwong LK, Van Deerlin VM, Lee VM, Trojanowski JQ. Robinson JL, et al. Among authors: kwong lk. Acta Neuropathol. 2013 Jan;125(1):121-31. doi: 10.1007/s00401-012-1055-8. Epub 2012 Nov 3. Acta Neuropathol. 2013. PMID: 23124365 Free PMC article.
Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion.
Brettschneider J, Van Deerlin VM, Robinson JL, Kwong L, Lee EB, Ali YO, Safren N, Monteiro MJ, Toledo JB, Elman L, McCluskey L, Irwin DJ, Grossman M, Molina-Porcel L, Lee VM, Trojanowski JQ. Brettschneider J, et al. Among authors: kwong l. Acta Neuropathol. 2012 Jun;123(6):825-39. doi: 10.1007/s00401-012-0970-z. Epub 2012 Mar 18. Acta Neuropathol. 2012. PMID: 22426854 Free PMC article.
341 results