Hofström C - Search Results

1

HAHAHA, HEHEHE, HIHIHI, or HKHKHK: influence of position and composition of histidine containing tags on biodistribution of [(99m)Tc(CO)3](+)-labeled affibody molecules.

Hofström C, Altai M, Honarvar H, Strand J, Malmberg J, Hosseinimehr SJ, Orlova A, Gräslund T, Tolmachev V. Hofström C, et al. J Med Chem. 2013 Jun 27;56(12):4966-74. doi: 10.1021/jm400218y. Epub 2013 Jun 14. J Med Chem. 2013. PMID: 23692562 Free article.

2

HEHEHE-tagged affibody molecule may be purified by IMAC, is conveniently labeled with [⁹⁹(m)Tc(CO)₃](+), and shows improved biodistribution with reduced hepatic radioactivity accumulation.

Tolmachev V, Hofström C, Malmberg J, Ahlgren S, Hosseinimehr SJ, Sandström M, Abrahmsén L, Orlova A, Gräslund T. Tolmachev V, et al. Among authors: hofstrom c. Bioconjug Chem. 2010 Nov 17;21(11):2013-22. doi: 10.1021/bc1002357. Epub 2010 Oct 22. Bioconjug Chem. 2010. PMID: 20964447

3

Use of a HEHEHE purification tag instead of a hexahistidine tag improves biodistribution of affibody molecules site-specifically labeled with (99m)Tc, (111)In, and (125)I.

Hofstrom C, Orlova A, Altai M, Wangsell F, Graslund T, Tolmachev V. Hofstrom C, et al. J Med Chem. 2011 Jun 9;54(11):3817-26. doi: 10.1021/jm200065e. Epub 2011 May 12. J Med Chem. 2011. PMID: 21524142

4

Novel antigen design for the generation of antibodies to G-protein-coupled receptors.

Larsson K, Hofström C, Lindskog C, Hansson M, Angelidou P, Hökfelt T, Uhlén M, Wernérus H, Gräslund T, Hober S. Larsson K, et al. Among authors: hofstrom c. J Immunol Methods. 2011 Jul 29;370(1-2):14-23. doi: 10.1016/j.jim.2011.05.001. Epub 2011 May 12. J Immunol Methods. 2011. PMID: 21605562

5

Imaging of insulinlike growth factor type 1 receptor in prostate cancer xenografts using the affibody molecule 111In-DOTA-ZIGF1R:4551.

Tolmachev V, Malmberg J, Hofström C, Abrahmsén L, Bergman T, Sjöberg A, Sandström M, Gräslund T, Orlova A. Tolmachev V, et al. Among authors: hofstrom c. J Nucl Med. 2012 Jan;53(1):90-7. doi: 10.2967/jnumed.111.090829. Epub 2011 Dec 15. J Nucl Med. 2012. PMID: 22173843 Free article.

6

Evaluation of a HER2-targeting affibody molecule combining an N-terminal HEHEHE-tag with a GGGC chelator for 99mTc-labelling at the C terminus.

Lindberg H, Hofström C, Altai M, Honorvar H, Wållberg H, Orlova A, Ståhl S, Gräslund T, Tolmachev V. Lindberg H, et al. Among authors: hofstrom c. Tumour Biol. 2012 Jun;33(3):641-51. doi: 10.1007/s13277-011-0305-z. Epub 2012 Jan 17. Tumour Biol. 2012. PMID: 22249974

7

[99mTc(CO)3]+-(HE)3-ZIGF1R:4551, a new Affibody conjugate for visualization of insulin-like growth factor-1 receptor expression in malignant tumours.

Orlova A, Hofström C, Strand J, Varasteh Z, Sandstrom M, Andersson K, Tolmachev V, Gräslund T. Orlova A, et al. Among authors: hofstrom c. Eur J Nucl Med Mol Imaging. 2013 Feb;40(3):439-49. doi: 10.1007/s00259-012-2284-8. Epub 2012 Nov 21. Eur J Nucl Med Mol Imaging. 2013. PMID: 23179942

8

Evaluation of 99mTc-Z IGF1R:4551-GGGC affibody molecule, a new probe for imaging of insulin-like growth factor type 1 receptor expression.

Mitran B, Altai M, Hofström C, Honarvar H, Sandström M, Orlova A, Tolmachev V, Gräslund T. Mitran B, et al. Among authors: hofstrom c. Amino Acids. 2015 Feb;47(2):303-15. doi: 10.1007/s00726-014-1859-z. Epub 2014 Nov 27. Amino Acids. 2015. PMID: 25425114 Free PMC article.

9

Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy.

Mortensen ACL, Berglund H, Segerström L, Walle M, Hofström C, Persson H, Nygren PÅ, Nilvebrant J, Frejd FY, Nestor M. Mortensen ACL, et al. Among authors: hofstrom c. Sci Rep. 2023 Nov 24;13(1):20648. doi: 10.1038/s41598-023-47891-2. Sci Rep. 2023. PMID: 38001360 Free PMC article.

10

Generation and validation of recombinant antibodies to study human aminoacyl-tRNA synthetases.

Preger C, Wigren E, Ossipova E, Marks C, Lengqvist J, Hofström C, Andersson O, Jakobsson PJ, Gräslund S, Persson H. Preger C, et al. Among authors: hofstrom c. J Biol Chem. 2020 Oct 9;295(41):13981-13993. doi: 10.1074/jbc.RA120.012893. Epub 2020 Aug 14. J Biol Chem. 2020. PMID: 32817337 Free PMC article.

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