Lampidis TJ - Search Results

1

Conversion of 2-deoxyglucose-induced growth inhibition to cell death in normoxic tumor cells.

Liu H, Kurtoglu M, Cao Y, Xi H, Kumar R, Axten JM, Lampidis TJ. Liu H, et al. Among authors: lampidis tj. Cancer Chemother Pharmacol. 2013 Jul;72(1):251-62. doi: 10.1007/s00280-013-2193-y. Epub 2013 May 23. Cancer Chemother Pharmacol. 2013. PMID: 23700291

2

Efficacy of 2-halogen substituted D-glucose analogs in blocking glycolysis and killing "hypoxic tumor cells".

Lampidis TJ, Kurtoglu M, Maher JC, Liu H, Krishan A, Sheft V, Szymanski S, Fokt I, Rudnicki WR, Ginalski K, Lesyng B, Priebe W. Lampidis TJ, et al. Cancer Chemother Pharmacol. 2006 Dec;58(6):725-34. doi: 10.1007/s00280-006-0207-8. Epub 2006 Mar 23. Cancer Chemother Pharmacol. 2006. PMID: 16555088

3

Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells.

Kurtoglu M, Maher JC, Lampidis TJ. Kurtoglu M, et al. Among authors: lampidis tj. Antioxid Redox Signal. 2007 Sep;9(9):1383-90. doi: 10.1089/ars.2007.1714. Antioxid Redox Signal. 2007. PMID: 17627467 Review.

4

Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with N-linked glycosylation.

Kurtoglu M, Gao N, Shang J, Maher JC, Lehrman MA, Wangpaichitr M, Savaraj N, Lane AN, Lampidis TJ. Kurtoglu M, et al. Among authors: lampidis tj. Mol Cancer Ther. 2007 Nov;6(11):3049-58. doi: 10.1158/1535-7163.MCT-07-0310. Mol Cancer Ther. 2007. PMID: 18025288

5

High endoplasmic reticulum activity renders multiple myeloma cells hypersensitive to mitochondrial inhibitors.

Kurtoglu M, Philips K, Liu H, Boise LH, Lampidis TJ. Kurtoglu M, et al. Among authors: lampidis tj. Cancer Chemother Pharmacol. 2010 May;66(1):129-40. doi: 10.1007/s00280-009-1143-1. Epub 2009 Sep 25. Cancer Chemother Pharmacol. 2010. PMID: 19779717 Free PMC article.

6

2-Deoxy-D-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion.

Xi H, Kurtoglu M, Liu H, Wangpaichitr M, You M, Liu X, Savaraj N, Lampidis TJ. Xi H, et al. Among authors: lampidis tj. Cancer Chemother Pharmacol. 2011 Apr;67(4):899-910. doi: 10.1007/s00280-010-1391-0. Epub 2010 Jul 1. Cancer Chemother Pharmacol. 2011. PMID: 20593179 Free PMC article.

7

Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy.

Xi H, Barredo JC, Merchan JR, Lampidis TJ. Xi H, et al. Among authors: lampidis tj. Biochem Pharmacol. 2013 May 15;85(10):1463-77. doi: 10.1016/j.bcp.2013.02.037. Epub 2013 Mar 13. Biochem Pharmacol. 2013. PMID: 23500541

8

Increased sensitivity to glucose starvation correlates with downregulation of glycogen phosphorylase isoform PYGB in tumor cell lines resistant to 2-deoxy-D-glucose.

Philips KB, Kurtoglu M, Leung HJ, Liu H, Gao N, Lehrman MA, Murray TG, Lampidis TJ. Philips KB, et al. Among authors: lampidis tj. Cancer Chemother Pharmacol. 2014 Feb;73(2):349-61. doi: 10.1007/s00280-013-2358-8. Epub 2013 Dec 1. Cancer Chemother Pharmacol. 2014. PMID: 24292700 Free PMC article.

9

Targeting cisplatin-resistant human tumor cells with metabolic inhibitors.

Sullivan EJ, Kurtoglu M, Brenneman R, Liu H, Lampidis TJ. Sullivan EJ, et al. Among authors: lampidis tj. Cancer Chemother Pharmacol. 2014 Feb;73(2):417-27. doi: 10.1007/s00280-013-2366-8. Epub 2013 Dec 19. Cancer Chemother Pharmacol. 2014. PMID: 24352250

10

Hypoxia increases tumor cell sensitivity to glycolytic inhibitors: a strategy for solid tumor therapy (Model C).

Liu H, Savaraj N, Priebe W, Lampidis TJ. Liu H, et al. Among authors: lampidis tj. Biochem Pharmacol. 2002 Dec 15;64(12):1745-51. doi: 10.1016/s0006-2952(02)01456-9. Biochem Pharmacol. 2002. PMID: 12445863

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