Burkhart CA - Search Results

1

3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole.

Macor JE, Burkhart CA, Heym JH, Ives JL, Lebel LA, Newman ME, Nielsen JA, Ryan K, Schulz DW, Torgersen LK, et al. Macor JE, et al. Among authors: burkhart ca. J Med Chem. 1990 Aug;33(8):2087-93. doi: 10.1021/jm00170a007. J Med Chem. 1990. PMID: 2374139

2

(+)-[3H]3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine binding to sigma receptors in mouse brain in vivo.

Koe BK, Burkhart CA, Lebel LA. Koe BK, et al. Among authors: burkhart ca. Eur J Pharmacol. 1989 Feb 28;161(2-3):263-6. doi: 10.1016/0014-2999(89)90857-1. Eur J Pharmacol. 1989. PMID: 2566491

3

Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation.

Naisbitt DJ, Farrell J, Gordon SF, Maggs JL, Burkhart C, Pichler WJ, Pirmohamed M, Park BK. Naisbitt DJ, et al. Mol Pharmacol. 2002 Sep;62(3):628-37. doi: 10.1124/mol.62.3.628. Mol Pharmacol. 2002. PMID: 12181439

4

Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo.

Naisbitt DJ, Gordon SF, Pirmohamed M, Burkhart C, Cribb AE, Pichler WJ, Park BK. Naisbitt DJ, et al. Br J Pharmacol. 2001 May;133(2):295-305. doi: 10.1038/sj.bjp.0704074. Br J Pharmacol. 2001. PMID: 11350866 Free PMC article.

5

Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals.

Schnyder B, Burkhart C, Schnyder-Frutig K, von Greyerz S, Naisbitt DJ, Pirmohamed M, Park BK, Pichler WJ. Schnyder B, et al. J Immunol. 2000 Jun 15;164(12):6647-54. doi: 10.4049/jimmunol.164.12.6647. J Immunol. 2000. PMID: 10843725

6

Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells.

Burkhart C, von Greyerz S, Depta JP, Naisbitt DJ, Britschgi M, Park KB, Pichler WJ. Burkhart C, et al. Br J Pharmacol. 2001 Feb;132(3):623-30. doi: 10.1038/sj.bjp.0703845. Br J Pharmacol. 2001. PMID: 11159714 Free PMC article.

7

Non-covalent presentation of sulfamethoxazole to human CD4+ T cells is independent of distinct human leucocyte antigen-bound peptides.

Burkhart C, Britschgi M, Strasser I, Depta JP, von Greyerz S, Barnaba V, Pichler WJ. Burkhart C, et al. Clin Exp Allergy. 2002 Nov;32(11):1635-43. doi: 10.1046/j.1365-2222.2002.01513.x. Clin Exp Allergy. 2002. PMID: 12569986

8

Molecular basis of drug recognition by specific T-cell receptors.

von Greyerz S, Burkhart C, Pichler WJ. von Greyerz S, et al. Int Arch Allergy Immunol. 1999 Jul;119(3):173-80. doi: 10.1159/000024192. Int Arch Allergy Immunol. 1999. PMID: 10436388 Review.

9

Molecular aspects of drug recognition by specific T cells.

Britschgi M, von Greyerz S, Burkhart C, Pichler WJ. Britschgi M, et al. Curr Drug Targets. 2003 Jan;4(1):1-11. doi: 10.2174/1389450033347082. Curr Drug Targets. 2003. PMID: 12528985 Review.

10

Drug interaction with T-cell receptors: T-cell receptor density determines degree of cross-reactivity.

Depta JP, Altznauer F, Gamerdinger K, Burkhart C, Weltzien HU, Pichler WJ. Depta JP, et al. J Allergy Clin Immunol. 2004 Mar;113(3):519-27. doi: 10.1016/j.jaci.2003.11.030. J Allergy Clin Immunol. 2004. PMID: 15007356

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