Rollema H - Search Results

1

In vivo intracerebral microdialysis studies in rats of MPP+ analogues and related charged species.

Rollema H, Johnson EA, Booth RG, Caldera P, Lampen P, Youngster SK, Trevor AJ, Naiman N, Castagnoli N Jr. Rollema H, et al. J Med Chem. 1990 Aug;33(8):2221-30. doi: 10.1021/jm00170a029. J Med Chem. 1990. PMID: 2374149

2

Intracerebral microdialysis neurotoxicity studies of quinoline and isoquinoline derivatives related to MPTP/MPP+.

Booth RG, Castagnoli N Jr, Rollema H. Booth RG, et al. Among authors: rollema h. Neurosci Lett. 1989 May 22;100(1-3):306-12. doi: 10.1016/0304-3940(89)90704-0. Neurosci Lett. 1989. PMID: 2788253

3

1-methyl-4-phenylpyridinium (MPP+) analogs: in vivo neurotoxicity and inhibition of striatal synaptosomal dopamine uptake.

Johnson EA, Wu EY, Rollema H, Booth RG, Trevor AJ, Castagnoli N Jr. Johnson EA, et al. Among authors: rollema h. Eur J Pharmacol. 1989 Jul 4;166(1):65-74. doi: 10.1016/0014-2999(89)90684-5. Eur J Pharmacol. 1989. PMID: 2806366

4

In vivo dopaminergic neurotoxicity of the 2-beta-methylcarbolinium ion, a potential endogenous MPP+ analog.

Rollema H, Booth RG, Castagnoli N Jr. Rollema H, et al. Eur J Pharmacol. 1988 Aug 9;153(1):131-4. doi: 10.1016/0014-2999(88)90597-3. Eur J Pharmacol. 1988. PMID: 3265107

5

MPP(+)-like neurotoxicity of a pyridinium metabolite derived from haloperidol: in vivo microdialysis and in vitro mitochondrial studies.

Rollema H, Skolnik M, D'Engelbronner J, Igarashi K, Usuki E, Castagnoli N Jr. Rollema H, et al. J Pharmacol Exp Ther. 1994 Jan;268(1):380-7. J Pharmacol Exp Ther. 1994. PMID: 8301579

6

Comparison of the effects of intracerebrally administered MPP+ (1-methyl-4-phenylpyridinium) in three species: microdialysis of dopamine and metabolites in mouse, rat and monkey striatum.

Rollema H, Alexander GM, Grothusen JR, Matos FF, Castagnoli N Jr. Rollema H, et al. Neurosci Lett. 1989 Dec 4;106(3):275-81. doi: 10.1016/0304-3940(89)90176-6. Neurosci Lett. 1989. PMID: 2601882

7

Studies on 4-benzyl-1-methyl-1,2,3,6-tetrahydropyridine, a nonneurotoxic analogue of the parkinsonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

Naiman N, Rollema H, Johnson E, Castagnoli N Jr. Naiman N, et al. Among authors: rollema h. Chem Res Toxicol. 1990 Mar-Apr;3(2):133-8. doi: 10.1021/tx00014a008. Chem Res Toxicol. 1990. PMID: 2130940

8

Identification of a potentially neurotoxic pyridinium metabolite of haloperidol in rats.

Subramanyam B, Rollema H, Woolf T, Castagnoli N Jr. Subramanyam B, et al. Among authors: rollema h. Biochem Biophys Res Commun. 1990 Jan 15;166(1):238-44. doi: 10.1016/0006-291x(90)91936-m. Biochem Biophys Res Commun. 1990. PMID: 2302206

9

MPP+-induced efflux of dopamine and lactate from rat striatum have similar time courses as shown by in vivo brain dialysis.

Rollema H, Kuhr WG, Kranenborg G, De Vries J, Van den Berg C. Rollema H, et al. J Pharmacol Exp Ther. 1988 Jun;245(3):858-66. J Pharmacol Exp Ther. 1988. PMID: 2455037

10

Synthesis and pharmacology of trans-4-n-propyl-3,4,4a,10b-tetrahydro-2H,5H-1-benzopyrano[4,3-b ]-1,4-oxazin-7- and -9-ols: the significance of nitrogen pKa values for central dopamine receptor activation.

Dijkstra D, Mulder TB, Rollema H, Tepper PG, Van der Weide J, Horn AS. Dijkstra D, et al. Among authors: rollema h. J Med Chem. 1988 Nov;31(11):2178-82. doi: 10.1021/jm00119a020. J Med Chem. 1988. PMID: 2903247

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