Degen J - Search Results

1

Inactivation of ceramide synthase 6 in mice results in an altered sphingolipid metabolism and behavioral abnormalities.

Ebel P, Vom Dorp K, Petrasch-Parwez E, Zlomuzica A, Kinugawa K, Mariani J, Minich D, Ginkel C, Welcker J, Degen J, Eckhardt M, Dere E, Dörmann P, Willecke K. Ebel P, et al. Among authors: degen j. J Biol Chem. 2013 Jul 19;288(29):21433-21447. doi: 10.1074/jbc.M113.479907. Epub 2013 Jun 12. J Biol Chem. 2013. PMID: 23760501 Free PMC article.

2

Adult ceramide synthase 2 (CERS2)-deficient mice exhibit myelin sheath defects, cerebellar degeneration, and hepatocarcinomas.

Imgrund S, Hartmann D, Farwanah H, Eckhardt M, Sandhoff R, Degen J, Gieselmann V, Sandhoff K, Willecke K. Imgrund S, et al. Among authors: degen j. J Biol Chem. 2009 Nov 27;284(48):33549-60. doi: 10.1074/jbc.M109.031971. Epub 2009 Sep 30. J Biol Chem. 2009. PMID: 19801672 Free PMC article.

3

Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes.

Ginkel C, Hartmann D, vom Dorp K, Zlomuzica A, Farwanah H, Eckhardt M, Sandhoff R, Degen J, Rabionet M, Dere E, Dörmann P, Sandhoff K, Willecke K. Ginkel C, et al. Among authors: degen j. J Biol Chem. 2012 Dec 7;287(50):41888-902. doi: 10.1074/jbc.M112.413500. Epub 2012 Oct 16. J Biol Chem. 2012. PMID: 23074226 Free PMC article.

4

Ceramide synthase 4 deficiency in mice causes lipid alterations in sebum and results in alopecia.

Ebel P, Imgrund S, Vom Dorp K, Hofmann K, Maier H, Drake H, Degen J, Dörmann P, Eckhardt M, Franz T, Willecke K. Ebel P, et al. Among authors: degen j. Biochem J. 2014 Jul 1;461(1):147-58. doi: 10.1042/BJ20131242. Biochem J. 2014. PMID: 24738593

5

Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity.

Gosejacob D, Jäger PS, Vom Dorp K, Frejno M, Carstensen AC, Köhnke M, Degen J, Dörmann P, Hoch M. Gosejacob D, et al. Among authors: degen j. J Biol Chem. 2016 Mar 25;291(13):6989-7003. doi: 10.1074/jbc.M115.691212. Epub 2016 Feb 7. J Biol Chem. 2016. PMID: 26853464 Free PMC article.

6

Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice.

Bickert A, Ginkel C, Kol M, vom Dorp K, Jastrow H, Degen J, Jacobs RL, Vance DE, Winterhager E, Jiang XC, Dörmann P, Somerharju P, Holthuis JC, Willecke K. Bickert A, et al. Among authors: degen j. J Lipid Res. 2015 Apr;56(4):821-35. doi: 10.1194/jlr.M055269. Epub 2015 Feb 9. J Lipid Res. 2015. PMID: 25667419 Free PMC article.

7

Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division.

Bickert A, Kern P, van Uelft M, Herresthal S, Ulas T, Gutbrod K, Breiden B, Degen J, Sandhoff K, Schultze JL, Dörmann P, Hartmann D, Bauer R, Willecke K. Bickert A, et al. Among authors: degen j. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jul;1863(7):734-749. doi: 10.1016/j.bbalip.2018.04.006. Epub 2018 Apr 10. Biochim Biophys Acta Mol Cell Biol Lipids. 2018. PMID: 29653252

8

Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans.

Tress O, Maglione M, Zlomuzica A, May D, Dicke N, Degen J, Dere E, Kettenmann H, Hartmann D, Willecke K. Tress O, et al. Among authors: degen j. PLoS Genet. 2011 Jul;7(7):e1002146. doi: 10.1371/journal.pgen.1002146. Epub 2011 Jul 7. PLoS Genet. 2011. PMID: 21750683 Free PMC article.

9

Expression pattern of lacZ reporter gene representing connexin36 in transgenic mice.

Degen J, Meier C, Van Der Giessen RS, Söhl G, Petrasch-Parwez E, Urschel S, Dermietzel R, Schilling K, De Zeeuw CI, Willecke K. Degen J, et al. J Comp Neurol. 2004 Jun 7;473(4):511-25. doi: 10.1002/cne.20085. J Comp Neurol. 2004. PMID: 15116387

10

Immunohistochemical detection of the neuronal connexin36 in the mouse central nervous system in comparison to connexin36-deficient tissues.

Meier C, Petrasch-Parwez E, Habbes HW, Teubner B, Güldenagel M, Degen J, Söhl G, Willecke K, Dermietzel R. Meier C, et al. Among authors: degen j. Histochem Cell Biol. 2002 Jun;117(6):461-71. doi: 10.1007/s00418-002-0417-z. Epub 2002 Jun 8. Histochem Cell Biol. 2002. PMID: 12107497

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