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A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction.
Zuccato C, Breda L, Salvatori F, Breveglieri G, Gardenghi S, Bianchi N, Brognara E, Lampronti I, Borgatti M, Rivella S, Gambari R. Zuccato C, et al. Among authors: salvatori f. Ann Hematol. 2012 Aug;91(8):1201-13. doi: 10.1007/s00277-012-1430-5. Epub 2012 Mar 31. Ann Hematol. 2012. PMID: 22460946 Free PMC article.
A novel frameshift mutation (+A) at codon 18 of the beta-globin gene associated with high persistence of fetal hemoglobin phenotype and deltabeta-thalassemia.
Feriotto G, Salvatori F, Finotti A, Breveglieri G, Venturi M, Zuccato C, Bianchi N, Borgatti M, Lampronti I, Mancini I, Massei F, Favre C, Gambari R. Feriotto G, et al. Among authors: salvatori f. Acta Haematol. 2008;119(1):28-37. doi: 10.1159/000114204. Epub 2008 Jan 30. Acta Haematol. 2008. PMID: 18230963
Bergamot (Citrus bergamia Risso) fruit extracts as γ-globin gene expression inducers: phytochemical and functional perspectives.
Guerrini A, Lampronti I, Bianchi N, Zuccato C, Breveglieri G, Salvatori F, Mancini I, Rossi D, Potenza R, Chiavilli F, Sacchetti G, Gambari R, Borgatti M. Guerrini A, et al. Among authors: salvatori f. J Agric Food Chem. 2009 May 27;57(10):4103-11. doi: 10.1021/jf803489p. Epub 2009 Apr 16. J Agric Food Chem. 2009. PMID: 19371028
Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β -Globin Gene with the IVSI-6 Thalassemia Mutation.
Breveglieri G, Mancini I, Bianchi N, Lampronti I, Salvatori F, Fabbri E, Zuccato C, Cosenza LC, Montagner G, Borgatti M, Altruda F, Fagoonee S, Carandina G, Rubini M, Aiello V, Breda L, Rivella S, Gambari R, Finotti A. Breveglieri G, et al. Among authors: salvatori f. Biomed Res Int. 2015;2015:687635. doi: 10.1155/2015/687635. Epub 2015 May 4. Biomed Res Int. 2015. PMID: 26097845 Free PMC article.
Development and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promoters.
Breveglieri G, Salvatori F, Finotti A, Cosenza LC, Zuccato C, Bianchi N, Breda L, Rivella S, Bresciani A, Bisbocci M, Borgatti M, Gambari R. Breveglieri G, et al. Among authors: salvatori f. Anal Bioanal Chem. 2019 Nov;411(29):7669-7680. doi: 10.1007/s00216-019-01959-z. Epub 2019 Jul 4. Anal Bioanal Chem. 2019. PMID: 31273412
Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations.
Salvatori F, Cantale V, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Breda L, Rivella S, Gambari R. Salvatori F, et al. Biotechnol Appl Biochem. 2009 Jul 9;54(1):41-52. doi: 10.1042/BA20080266. Biotechnol Appl Biochem. 2009. PMID: 19216718 Free PMC article.
158 results