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Mice with an adipocyte-specific lipin 1 separation-of-function allele reveal unexpected roles for phosphatidic acid in metabolic regulation.
Mitra MS, Chen Z, Ren H, Harris TE, Chambers KT, Hall AM, Nadra K, Klein S, Chrast R, Su X, Morris AJ, Finck BN. Mitra MS, et al. Among authors: chrast r. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):642-7. doi: 10.1073/pnas.1213493110. Epub 2012 Dec 24. Proc Natl Acad Sci U S A. 2013. PMID: 23267081 Free PMC article.
Macrophage-Associated Lipin-1 Enzymatic Activity Contributes to Modified Low-Density Lipoprotein-Induced Proinflammatory Signaling and Atherosclerosis.
Vozenilek AE, Navratil AR, Green JM, Coleman DT, Blackburn CMR, Finney AC, Pearson BH, Chrast R, Finck BN, Klein RL, Orr AW, Woolard MD. Vozenilek AE, et al. Among authors: chrast r. Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):324-334. doi: 10.1161/ATVBAHA.117.310455. Epub 2017 Dec 7. Arterioscler Thromb Vasc Biol. 2018. PMID: 29217509 Free PMC article.
Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice.
Schweitzer GG, Collier SL, Chen Z, McCommis KS, Pittman SK, Yoshino J, Matkovich SJ, Hsu FF, Chrast R, Eaton JM, Harris TE, Weihl CC, Finck BN. Schweitzer GG, et al. Among authors: chrast r. FASEB J. 2019 Jan;33(1):652-667. doi: 10.1096/fj.201800361R. Epub 2018 Jul 20. FASEB J. 2019. PMID: 30028636 Free PMC article.
K., Yoshino, J., Matkovich, S. J., Hsu, F.-F., Chrast, R., Eaton, J. M., Harris, T. E., Weihl, C. C., Finck, B. N. Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice....
K., Yoshino, J., Matkovich, S. J., Hsu, F.-F., Chrast, R., Eaton, J. M., Harris, T. E., Weihl, C. C., Finck, B. N. Loss of lip …
The glucocorticoid-induced leucine zipper (gilz/Tsc22d3-2) gene locus plays a crucial role in male fertility.
Suarez PE, Rodriguez EG, Soundararajan R, Mérillat AM, Stehle JC, Rotman S, Roger T, Voirol MJ, Wang J, Gross O, Pétrilli V, Nadra K, Wilson A, Beermann F, Pralong FP, Maillard M, Pearce D, Chrast R, Rossier BC, Hummler E. Suarez PE, et al. Among authors: chrast r. Mol Endocrinol. 2012 Jun;26(6):1000-13. doi: 10.1210/me.2011-1249. Epub 2012 May 3. Mol Endocrinol. 2012. PMID: 22556341 Free PMC article.
Epineurial adipocytes are dispensable for Schwann cell myelination.
Nadra K, Médard JJ, Quignodon L, Verheijen MH, Desvergne B, Chrast R. Nadra K, et al. Among authors: chrast r. J Neurochem. 2012 Dec;123(5):662-7. doi: 10.1111/j.1471-4159.2012.07896.x. Epub 2012 Oct 10. J Neurochem. 2012. PMID: 22849425 Free article.
Phosphatidic acid mediates demyelination in Lpin1 mutant mice.
Nadra K, de Preux Charles AS, Médard JJ, Hendriks WT, Han GS, Grès S, Carman GM, Saulnier-Blache JS, Verheijen MH, Chrast R. Nadra K, et al. Among authors: chrast r. Genes Dev. 2008 Jun 15;22(12):1647-61. doi: 10.1101/gad.1638008. Genes Dev. 2008. PMID: 18559480 Free PMC article.
85 results