Urtti A - Search Results

1

Challenges of using in vitro data for modeling P-glycoprotein efflux in the blood-brain barrier.

Sjöstedt N, Kortejärvi H, Kidron H, Vellonen KS, Urtti A, Yliperttula M. Sjöstedt N, et al. Among authors: urtti a. Pharm Res. 2014 Jan;31(1):1-19. doi: 10.1007/s11095-013-1124-2. Pharm Res. 2014. PMID: 23797466 Review.

2

Paracellular and passive transcellular permeability in immortalized human corneal epithelial cell culture model.

Toropainen E, Ranta VP, Vellonen KS, Palmgrén J, Talvitie A, Laavola M, Suhonen P, Hämäläinen KM, Auriola S, Urtti A. Toropainen E, et al. Among authors: urtti a. Eur J Pharm Sci. 2003 Sep;20(1):99-106. doi: 10.1016/s0928-0987(03)00173-8. Eur J Pharm Sci. 2003. PMID: 13678798

3

Ocular pharmacokinetic modeling using corneal absorption and desorption rates from in vitro permeation experiments with cultured corneal epithelial cells.

Ranta VP, Laavola M, Toropainen E, Vellonen KS, Talvitie A, Urtti A. Ranta VP, et al. Among authors: urtti a. Pharm Res. 2003 Sep;20(9):1409-16. doi: 10.1023/a:1025754026449. Pharm Res. 2003. PMID: 14567635

4

Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity.

Vellonen KS, Honkakoski P, Urtti A. Vellonen KS, et al. Among authors: urtti a. Eur J Pharm Sci. 2004 Oct;23(2):181-8. doi: 10.1016/j.ejps.2004.07.006. Eur J Pharm Sci. 2004. PMID: 15451006

5

Epidermal cell culture model with tight stratum corneum as a tool for dermal gene delivery studies.

Paasonen L, Korhonen M, Yliperttula M, Urtti A. Paasonen L, et al. Among authors: urtti a. Int J Pharm. 2006 Jan 13;307(2):188-93. doi: 10.1016/j.ijpharm.2005.09.032. Epub 2005 Nov 16. Int J Pharm. 2006. PMID: 16297582

6

Level A in vitro-in vivo correlation (IVIVC) model with Bayesian approach to formulation series.

Kortejärvi H, Malkki J, Marvola M, Urtti A, Yliperttula M, Pajunen P. Kortejärvi H, et al. Among authors: urtti a. J Pharm Sci. 2006 Jul;95(7):1595-605. doi: 10.1002/jps.20592. J Pharm Sci. 2006. PMID: 16732564

7

Computational prediction of oral drug absorption based on absorption rate constants in humans.

Linnankoski J, Mäkelä JM, Ranta VP, Urtti A, Yliperttula M. Linnankoski J, et al. Among authors: urtti a. J Med Chem. 2006 Jun 15;49(12):3674-81. doi: 10.1021/jm051231p. J Med Chem. 2006. PMID: 16759110

8

Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics.

Mannermaa E, Vellonen KS, Urtti A. Mannermaa E, et al. Among authors: urtti a. Adv Drug Deliv Rev. 2006 Nov 15;58(11):1136-63. doi: 10.1016/j.addr.2006.07.024. Epub 2006 Sep 16. Adv Drug Deliv Rev. 2006. PMID: 17081648 Review.

9

Pharmacokinetic simulation of biowaiver criteria: the effects of gastric emptying, dissolution, absorption and elimination rates.

Kortejärvi H, Urtti A, Yliperttula M. Kortejärvi H, et al. Among authors: urtti a. Eur J Pharm Sci. 2007 Feb;30(2):155-66. doi: 10.1016/j.ejps.2006.10.011. Epub 2006 Nov 11. Eur J Pharm Sci. 2007. PMID: 17187967

10

Effect of cell differentiation and passage number on the expression of efflux proteins in wild type and vinblastine-induced Caco-2 cell lines.

Siissalo S, Laitinen L, Koljonen M, Vellonen KS, Kortejärvi H, Urtti A, Hirvonen J, Kaukonen AM. Siissalo S, et al. Among authors: urtti a. Eur J Pharm Biopharm. 2007 Sep;67(2):548-54. doi: 10.1016/j.ejpb.2007.03.017. Epub 2007 Mar 28. Eur J Pharm Biopharm. 2007. PMID: 17475454

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