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Development and preclinical characterization of a humanized antibody targeting CXCL12.
Zhong C, Wang J, Li B, Xiang H, Ultsch M, Coons M, Wong T, Chiang NY, Clark S, Clark R, Quintana L, Gribling P, Suto E, Barck K, Corpuz R, Yao J, Takkar R, Lee WP, Damico-Beyer LA, Carano RD, Adams C, Kelley RF, Wang W, Ferrara N. Zhong C, et al. Among authors: ultsch m. Clin Cancer Res. 2013 Aug 15;19(16):4433-45. doi: 10.1158/1078-0432.CCR-13-0943. Epub 2013 Jun 28. Clin Cancer Res. 2013. PMID: 23812669
Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice.
Brightbill HD, Jeet S, Lin Z, Yan D, Zhou M, Tan M, Nguyen A, Yeh S, Delarosa D, Leong SR, Wong T, Chen Y, Ultsch M, Luis E, Ramani SR, Jackman J, Gonzalez L, Dennis MS, Chuntharapai A, DeForge L, Meng YG, Xu M, Eigenbrot C, Lee WP, Refino CJ, Balazs M, Wu LC. Brightbill HD, et al. Among authors: ultsch m. J Clin Invest. 2010 Jun;120(6):2218-29. doi: 10.1172/JCI40141. Epub 2010 May 10. J Clin Invest. 2010. PMID: 20458139 Free PMC article.
Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.
Pantua H, Diao J, Ultsch M, Hazen M, Mathieu M, McCutcheon K, Takeda K, Date S, Cheung TK, Phung Q, Hass P, Arnott D, Hongo JA, Matthews DJ, Brown A, Patel AH, Kelley RF, Eigenbrot C, Kapadia SB. Pantua H, et al. Among authors: ultsch m. J Mol Biol. 2013 Jun 12;425(11):1899-1914. doi: 10.1016/j.jmb.2013.02.025. Epub 2013 Feb 28. J Mol Biol. 2013. PMID: 23458406 Free article.
Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin.
Ultsch M, Li B, Maurer T, Mathieu M, Adolfsson O, Muhs A, Pfeifer A, Pihlgren M, Bainbridge TW, Reichelt M, Ernst JA, Eigenbrot C, Fuh G, Atwal JK, Watts RJ, Wang W. Ultsch M, et al. Sci Rep. 2016 Dec 20;6:39374. doi: 10.1038/srep39374. Sci Rep. 2016. PMID: 27996029 Free PMC article.
86 results