O'Reilly P - Search Results

1

Distinct roles for Ste20-like kinase SLK in muscle function and regeneration.

Storbeck CJ, Al-Zahrani KN, Sriram R, Kawesa S, O'Reilly P, Daniel K, McKay M, Kothary R, Tsilfidis C, Sabourin LA. Storbeck CJ, et al. Skelet Muscle. 2013 Jul 1;3(1):16. doi: 10.1186/2044-5040-3-16. Skelet Muscle. 2013. PMID: 23815977 Free PMC article.

2

The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility.

Roovers K, Wagner S, Storbeck CJ, O'Reilly P, Lo V, Northey JJ, Chmielecki J, Muller WJ, Siegel PM, Sabourin LA. Roovers K, et al. Oncogene. 2009 Aug 6;28(31):2839-48. doi: 10.1038/onc.2009.146. Epub 2009 Jun 15. Oncogene. 2009. PMID: 19525980

3

SLK-mediated phosphorylation of paxillin is required for focal adhesion turnover and cell migration.

Quizi JL, Baron K, Al-Zahrani KN, O'Reilly P, Sriram RK, Conway J, Laurin AA, Sabourin LA. Quizi JL, et al. Oncogene. 2013 Sep 26;32(39):4656-63. doi: 10.1038/onc.2012.488. Epub 2012 Nov 5. Oncogene. 2013. PMID: 23128389

4

The Ste20-like kinase SLK is required for cell cycle progression through G2.

O'Reilly PG, Wagner S, Franks DJ, Cailliau K, Browaeys E, Dissous C, Sabourin LA. O'Reilly PG, et al. J Biol Chem. 2005 Dec 23;280(51):42383-90. doi: 10.1074/jbc.M510763200. Epub 2005 Oct 18. J Biol Chem. 2005. PMID: 16236704 Free article.

5

v-Src-dependent down-regulation of the Ste20-like kinase SLK by casein kinase II.

Chaar Z, O'reilly P, Gelman I, Sabourin LA. Chaar Z, et al. J Biol Chem. 2006 Sep 22;281(38):28193-9. doi: 10.1074/jbc.M605665200. Epub 2006 Jul 12. J Biol Chem. 2006. PMID: 16837460 Free article.

6

The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration.

Storbeck CJ, Wagner S, O'Reilly P, McKay M, Parks RJ, Westphal H, Sabourin LA. Storbeck CJ, et al. Mol Biol Cell. 2009 Oct;20(19):4174-82. doi: 10.1091/mbc.e08-07-0707. Epub 2009 Aug 12. Mol Biol Cell. 2009. PMID: 19675209 Free PMC article.

7

Association of the Ste20-like kinase (SLK) with the microtubule. Role in Rac1-mediated regulation of actin dynamics during cell adhesion and spreading.

Wagner S, Flood TA, O'Reilly P, Hume K, Sabourin LA. Wagner S, et al. J Biol Chem. 2002 Oct 4;277(40):37685-92. doi: 10.1074/jbc.M205899200. Epub 2002 Jul 31. J Biol Chem. 2002. PMID: 12151406 Free article.

8

LDL-R promoting activity of peptides derived from human PCSK9 catalytic domain (153-421): design, synthesis and biochemical evaluation.

Alghamdi RH, O'Reilly P, Lu C, Gomes J, Lagace TA, Basak A. Alghamdi RH, et al. Eur J Med Chem. 2015 Mar 6;92:890-907. doi: 10.1016/j.ejmech.2015.01.022. Epub 2015 Jan 12. Eur J Med Chem. 2015. PMID: 25679794

9

Enediynyl peptides and iso-coumarinyl methyl sulfones as inhibitors of proprotein convertases PCSK8/SKI-1/S1P and PCSK4/PC4: Design, synthesis and biological evaluations.

Basak A, Goswami M, Rajkumar A, Mitra T, Majumdar S, O'Reilly P, Bdour HM, Trudeau VL, Basak A. Basak A, et al. Bioorg Med Chem Lett. 2015;25(10):2225-37. doi: 10.1016/j.bmcl.2015.03.029. Epub 2015 Mar 23. Bioorg Med Chem Lett. 2015. PMID: 25881830

10

RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer.

Khawaja H, Campbell A, Roberts JZ, Javadi A, O'Reilly P, McArt D, Allen WL, Majkut J, Rehm M, Bardelli A, Di Nicolantonio F, Scott CJ, Kennedy R, Vitale N, Harrison T, Sansom OJ, Longley DB, Evergren E, Van Schaeybroeck S. Khawaja H, et al. Cell Death Dis. 2020 Oct 29;11(10):930. doi: 10.1038/s41419-020-03131-3. Cell Death Dis. 2020. PMID: 33122623 Free PMC article.

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