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3-aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice.
Xi MY, Jia JM, Sun HP, Sun ZY, Jiang JW, Wang YJ, Zhang MY, Zhu JF, Xu LL, Jiang ZY, Xue X, Ye M, Yang X, Gao Y, Tao L, Guo XK, Xu XL, Guo QL, Zhang XJ, Hu R, You QD. Xi MY, et al. Among authors: xue x. J Med Chem. 2013 Oct 24;56(20):7925-38. doi: 10.1021/jm400944k. Epub 2013 Oct 9. J Med Chem. 2013. PMID: 24053646
Discovery of 1-(Phenylsulfonyl)-1,2,3,4-tetrahydroquinoline Derivative as Orally Bioavailable and Safe RORγt Inverse Agonists for Potential Treatment of Rheumatoid Arthritis.
Sun SL, Xu HJ, Jiang XL, Zhou J, Shi W, Wang XJ, Song W, Chang XY, Ma XQ, Zou XF, Wu SH, Yang J, Li QQ, Wang ZX, Cai J, Yu SP, Wang QX, Wei TH, Wu JZ, Tong ZJ, Zhou Y, Wang YB, Yu YC, Leng XJ, Ding N, Shi ZH, Dai WC, Xue X, Li NG, Wang XL. Sun SL, et al. Among authors: xue x. J Med Chem. 2024 Nov 28;67(22):20315-20342. doi: 10.1021/acs.jmedchem.4c01727. Epub 2024 Nov 15. J Med Chem. 2024. PMID: 39546350
Design and synthesis of selective FLT3 inhibitors via exploration of back pocket II.
Wang QX, Cao YH, Yang LJ, Ma YY, Li N, Wu SH, Chen L, Wu JZ, Tong ZJ, Wang XL, Xue X, Ding N, Leng XJ, Chang L, Dai WC, Yu YC, Sun SL, Yang Y, Li NG, Shi ZH. Wang QX, et al. Among authors: xue x. Future Med Chem. 2023 Jan;15(1):57-71. doi: 10.4155/fmc-2022-0231. Epub 2023 Jan 18. Future Med Chem. 2023. PMID: 36651264
5,590 results