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WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki J, Oka Y. Yamada T, et al. Among authors: katagiri h. Hum Mol Genet. 2006 May 15;15(10):1600-9. doi: 10.1093/hmg/ddl081. Epub 2006 Mar 28. Hum Mol Genet. 2006. PMID: 16571599
781 results