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The polymorphic linker domain of pfmdr1 is associated with resistance-conferring mutations in Plasmodium falciparum populations from East and West Africa.
Okombo J, Zongo I, Gadalla N, Bousema T, Beshir KB, Roper C, Hallett R, Ochola-Oyier LI, Sutherland CJ. Okombo J, et al. Among authors: hallett r. Antimicrob Agents Chemother. 2013 Sep;57(9):4595-8. doi: 10.1128/AAC.00455-13. Epub 2013 Jul 8. Antimicrob Agents Chemother. 2013. PMID: 23836177 Free PMC article.
Amodiaquine and artemether-lumefantrine select distinct alleles of the Plasmodium falciparum mdr1 gene in Tanzanian children treated for uncomplicated malaria.
Humphreys GS, Merinopoulos I, Ahmed J, Whitty CJ, Mutabingwa TK, Sutherland CJ, Hallett RL. Humphreys GS, et al. Among authors: hallett rl. Antimicrob Agents Chemother. 2007 Mar;51(3):991-7. doi: 10.1128/AAC.00875-06. Epub 2006 Dec 28. Antimicrob Agents Chemother. 2007. PMID: 17194834 Free PMC article. Clinical Trial.
The Mu subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine.
Henriques G, van Schalkwyk DA, Burrow R, Warhurst DC, Thompson E, Baker DA, Fidock DA, Hallett R, Flueck C, Sutherland CJ. Henriques G, et al. Among authors: hallett r. Antimicrob Agents Chemother. 2015 May;59(5):2540-7. doi: 10.1128/AAC.04067-14. Epub 2015 Feb 17. Antimicrob Agents Chemother. 2015. PMID: 25691625 Free PMC article.
Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT.
Henriques G, Hallett RL, Beshir KB, Gadalla NB, Johnson RE, Burrow R, van Schalkwyk DA, Sawa P, Omar SA, Clark TG, Bousema T, Sutherland CJ. Henriques G, et al. Among authors: hallett rl. J Infect Dis. 2014 Dec 15;210(12):2001-8. doi: 10.1093/infdis/jiu358. Epub 2014 Jul 3. J Infect Dis. 2014. PMID: 24994911 Free PMC article.
198 results