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The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia.
Schaaf MB, Cojocari D, Keulers TG, Jutten B, Starmans MH, de Jong MC, Begg AC, Savelkouls KG, Bussink J, Vooijs M, Wouters BG, Rouschop KM. Schaaf MB, et al. Among authors: jutten b. Radiother Oncol. 2013 Sep;108(3):529-34. doi: 10.1016/j.radonc.2013.06.015. Epub 2013 Jul 9. Radiother Oncol. 2013. PMID: 23849170
Proteomic analysis of gene expression following hypoxia and reoxygenation reveals proteins involved in the recovery from endoplasmic reticulum and oxidative stress.
Magagnin MG, Sergeant K, van den Beucken T, Rouschop KM, Jutten B, Seigneuric R, Lambin P, Devreese B, Koritzinsky M, Wouters BG. Magagnin MG, et al. Among authors: jutten b. Radiother Oncol. 2007 Jun;83(3):340-5. doi: 10.1016/j.radonc.2007.04.027. Epub 2007 May 24. Radiother Oncol. 2007. PMID: 17531340
Translational control is a major contributor to hypoxia induced gene expression.
van den Beucken T, Magagnin MG, Jutten B, Seigneuric R, Lambin P, Koritzinsky M, Wouters BG. van den Beucken T, et al. Among authors: jutten b. Radiother Oncol. 2011 Jun;99(3):379-84. doi: 10.1016/j.radonc.2011.05.058. Epub 2011 Jun 28. Radiother Oncol. 2011. PMID: 21719133 Free article.
Canonical autophagy does not contribute to cellular radioresistance.
Schaaf MB, Jutten B, Keulers TG, Savelkouls KG, Peeters HJ, van den Beucken T, van Schooten FJ, Godschalk RW, Vooijs M, Rouschop KM. Schaaf MB, et al. Among authors: jutten b. Radiother Oncol. 2015 Mar;114(3):406-12. doi: 10.1016/j.radonc.2015.02.019. Epub 2015 Mar 13. Radiother Oncol. 2015. PMID: 25779723
GABARAPL1 is required for increased EGFR membrane expression during hypoxia.
Keulers TG, Schaaf MB, Peeters HJ, Savelkouls KG, Vooijs MA, Bussink J, Jutten B, Rouschop KM. Keulers TG, et al. Among authors: jutten b. Radiother Oncol. 2015 Sep;116(3):417-22. doi: 10.1016/j.radonc.2015.06.023. Epub 2015 Jul 8. Radiother Oncol. 2015. PMID: 26164772
20 results