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Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Aβ metabolism.
Leal MC, Surace EI, Holgado MP, Ferrari CC, Tarelli R, Pitossi F, Wisniewski T, Castaño EM, Morelli L. Leal MC, et al. Among authors: castano em. Biochim Biophys Acta. 2012 Feb;1823(2):227-35. doi: 10.1016/j.bbamcr.2011.09.014. Epub 2011 Oct 19. Biochim Biophys Acta. 2012. PMID: 22036964 Free PMC article.
Worsening of memory deficit induced by energy-dense diet in a rat model of early-Alzheimer's disease is associated to neurotoxic Aβ species and independent of neuroinflammation.
Martino Adami PV, Galeano P, Wallinger ML, Quijano C, Rabossi A, Pagano ES, Olivar N, Reyes Toso C, Cardinali D, Brusco LI, Do Carmo S, Radi R, Gevorkian G, Castaño EM, Cuello AC, Morelli L. Martino Adami PV, et al. Among authors: castano em. Biochim Biophys Acta Mol Basis Dis. 2017 Mar;1863(3):731-743. doi: 10.1016/j.bbadis.2016.12.014. Epub 2016 Dec 27. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28039031 Free article.
Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer.
Galeano P, Leal MC, Ferrari CC, Dalmasso MC, Martino Adami PV, Farías MI, Casabona JC, Puntel M, Do Carmo S, Smal C, Arán M, Castaño EM, Pitossi FJ, Cuello AC, Morelli L. Galeano P, et al. Among authors: castano em. Mol Neurobiol. 2018 Nov;55(11):8637-8650. doi: 10.1007/s12035-018-1002-3. Epub 2018 Mar 26. Mol Neurobiol. 2018. PMID: 29582397
99 results