Almen MS - Search Results

1

Polymorphisms in FTO and near TMEM18 associate with type 2 diabetes and predispose to younger age at diagnosis of diabetes.

Kalnina I, Zaharenko L, Vaivade I, Rovite V, Nikitina-Zake L, Peculis R, Fridmanis D, Geldnere K, Jacobsson JA, Almen MS, Pirags V, Schiöth HB, Klovins J. Kalnina I, et al. Among authors: almen ms. Gene. 2013 Sep 25;527(2):462-8. doi: 10.1016/j.gene.2013.06.079. Epub 2013 Jul 13. Gene. 2013. PMID: 23860325

2

Genome-wide analysis reveals DNA methylation markers that vary with both age and obesity.

Almén MS, Nilsson EK, Jacobsson JA, Kalnina I, Klovins J, Fredriksson R, Schiöth HB. Almén MS, et al. Gene. 2014 Sep 10;548(1):61-7. doi: 10.1016/j.gene.2014.07.009. Epub 2014 Jul 8. Gene. 2014. PMID: 25010727 Free article.

3

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes.

Almén MS, Jacobsson JA, Moschonis G, Benedict C, Chrousos GP, Fredriksson R, Schiöth HB. Almén MS, et al. Genomics. 2012 Mar;99(3):132-7. doi: 10.1016/j.ygeno.2011.12.007. Epub 2012 Jan 2. Genomics. 2012. PMID: 22234326 Free article.

4

Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory context.

Rask-Andersen M, Almén MS, Schiöth HB. Rask-Andersen M, et al. Among authors: almen ms. Hum Genet. 2015 Nov;134(11-12):1183-93. doi: 10.1007/s00439-015-1599-5. Epub 2015 Sep 4. Hum Genet. 2015. PMID: 26340902

5

Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers.

Voisin S, Almén MS, Zheleznyakova GY, Lundberg L, Zarei S, Castillo S, Eriksson FE, Nilsson EK, Blüher M, Böttcher Y, Kovacs P, Klovins J, Rask-Andersen M, Schiöth HB. Voisin S, et al. Among authors: almen ms. Genome Med. 2015 Oct 8;7:103. doi: 10.1186/s13073-015-0225-4. Genome Med. 2015. PMID: 26449484 Free PMC article.

6

Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly.

Jacobsson JA, Almén MS, Benedict C, Hedberg LA, Michaëlsson K, Brooks S, Kullberg J, Axelsson T, Johansson L, Ahlström H, Fredriksson R, Lind L, Schiöth HB. Jacobsson JA, et al. Among authors: almen ms. PLoS One. 2011;6(5):e20158. doi: 10.1371/journal.pone.0020158. Epub 2011 May 27. PLoS One. 2011. PMID: 21637715 Free PMC article.

7

The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children.

Almén MS, Jacobsson JA, Shaik JH, Olszewski PK, Cedernaes J, Alsiö J, Sreedharan S, Levine AS, Fredriksson R, Marcus C, Schiöth HB. Almén MS, et al. BMC Med Genet. 2010 Apr 9;11:58. doi: 10.1186/1471-2350-11-58. BMC Med Genet. 2010. PMID: 20380707 Free PMC article.

8

Remarkable similarities between the hemichordate (Saccoglossus kowalevskii) and vertebrate GPCR repertoire.

Krishnan A, Almén MS, Fredriksson R, Schiöth HB. Krishnan A, et al. Among authors: almen ms. Gene. 2013 Sep 10;526(2):122-33. doi: 10.1016/j.gene.2013.05.005. Epub 2013 May 15. Gene. 2013. PMID: 23685280

9

Association of the LINGO2-related SNP rs10968576 with body mass in a cohort of elderly Swedes.

Rask-Andersen M, Almén MS, Lind L, Schiöth HB. Rask-Andersen M, et al. Among authors: almen ms. Mol Genet Genomics. 2015 Aug;290(4):1485-91. doi: 10.1007/s00438-015-1009-7. Epub 2015 Feb 25. Mol Genet Genomics. 2015. PMID: 25711307

10

Functional coupling analysis suggests link between the obesity gene FTO and the BDNF-NTRK2 signaling pathway.

Rask-Andersen M, Almén MS, Olausen HR, Olszewski PK, Eriksson J, Chavan RA, Levine AS, Fredriksson R, Schiöth HB. Rask-Andersen M, et al. Among authors: almen ms. BMC Neurosci. 2011 Nov 16;12:117. doi: 10.1186/1471-2202-12-117. BMC Neurosci. 2011. PMID: 22087873 Free PMC article.

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