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The new compound GET73, N-[(4-trifluoromethyl)benzyl]4-methoxybutyramide, Regulates hippocampal Aminoacidergic transmission possibly via an allosteric modulation of mGlu5 receptor. Behavioural evidence of its "anti-alcohol" and anxiolytic properties.
Ferraro L, Loche A, Beggiato S, Tomasini MC, Antonelli T, Colombo G, Lobina C, Carai MA, Porcu A, Castelli MP, Clerici F, Borelli AC, Cacciaglia R, Tanganelli S. Ferraro L, et al. Among authors: tomasini mc. Curr Med Chem. 2013;20(27):3339-57. doi: 10.2174/09298673113209990167. Curr Med Chem. 2013. PMID: 23862615 Review.
66 results