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Page 1
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia.
Laviolette M, Gossage DL, Gauvreau G, Leigh R, Olivenstein R, Katial R, Busse WW, Wenzel S, Wu Y, Datta V, Kolbeck R, Molfino NA. Laviolette M, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2013 Nov;132(5):1086-1096.e5. doi: 10.1016/j.jaci.2013.05.020. Epub 2013 Jul 16. J Allergy Clin Immunol. 2013. PMID: 23866823 Free PMC article. Clinical Trial.
Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging study.
Castro M, Wenzel SE, Bleecker ER, Pizzichini E, Kuna P, Busse WW, Gossage DL, Ward CK, Wu Y, Wang B, Khatry DB, van der Merwe R, Kolbeck R, Molfino NA, Raible DG. Castro M, et al. Among authors: kolbeck r. Lancet Respir Med. 2014 Nov;2(11):879-890. doi: 10.1016/S2213-2600(14)70201-2. Epub 2014 Oct 8. Lancet Respir Med. 2014. PMID: 25306557 Clinical Trial.
Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma.
Busse WW, Katial R, Gossage D, Sari S, Wang B, Kolbeck R, Coyle AJ, Koike M, Spitalny GL, Kiener PA, Geba GP, Molfino NA. Busse WW, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2010 Jun;125(6):1237-1244.e2. doi: 10.1016/j.jaci.2010.04.005. J Allergy Clin Immunol. 2010. PMID: 20513521 Clinical Trial.
MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function.
Kolbeck R, Kozhich A, Koike M, Peng L, Andersson CK, Damschroder MM, Reed JL, Woods R, Dall'acqua WW, Stephens GL, Erjefalt JS, Bjermer L, Humbles AA, Gossage D, Wu H, Kiener PA, Spitalny GL, Mackay CR, Molfino NA, Coyle AJ. Kolbeck R, et al. J Allergy Clin Immunol. 2010 Jun;125(6):1344-1353.e2. doi: 10.1016/j.jaci.2010.04.004. J Allergy Clin Immunol. 2010. PMID: 20513525
Novel targeted therapies for eosinophilic disorders.
Wechsler ME, Fulkerson PC, Bochner BS, Gauvreau GM, Gleich GJ, Henkel T, Kolbeck R, Mathur SK, Ortega H, Patel J, Prussin C, Renzi P, Rothenberg ME, Roufosse F, Simon D, Simon HU, Wardlaw A, Weller PF, Klion AD. Wechsler ME, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2012 Sep;130(3):563-71. doi: 10.1016/j.jaci.2012.07.027. J Allergy Clin Immunol. 2012. PMID: 22935585 Free PMC article. Review.
Lifelong memory responses perpetuate humoral TH2 immunity and anaphylaxis in food allergy.
Jiménez-Saiz R, Chu DK, Mandur TS, Walker TD, Gordon ME, Chaudhary R, Koenig J, Saliba S, Galipeau HJ, Utley A, King IL, Lee K, Ettinger R, Waserman S, Kolbeck R, Jordana M. Jiménez-Saiz R, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2017 Dec;140(6):1604-1615.e5. doi: 10.1016/j.jaci.2017.01.018. Epub 2017 Feb 16. J Allergy Clin Immunol. 2017. PMID: 28216433 Free PMC article.
Benralizumab for PDGFRA-Negative Hypereosinophilic Syndrome.
Kuang FL, Legrand F, Makiya M, Ware J, Wetzler L, Brown T, Magee T, Piligian B, Yoon P, Ellis JH, Sun X, Panch SR, Powers A, Alao H, Kumar S, Quezado M, Yan L, Lee N, Kolbeck R, Newbold P, Goldman M, Fay MP, Khoury P, Maric I, Klion AD. Kuang FL, et al. Among authors: kolbeck r. N Engl J Med. 2019 Apr 4;380(14):1336-1346. doi: 10.1056/NEJMoa1812185. N Engl J Med. 2019. PMID: 30943337 Free PMC article. Clinical Trial.
IL-5 receptor α levels in patients with marked eosinophilia or mastocytosis.
Wilson TM, Maric I, Shukla J, Brown M, Santos C, Simakova O, Khoury P, Fay MP, Kozhich A, Kolbeck R, Metcalfe DD, Klion AD. Wilson TM, et al. Among authors: kolbeck r. J Allergy Clin Immunol. 2011 Nov;128(5):1086-92.e1-3. doi: 10.1016/j.jaci.2011.05.032. Epub 2011 Jul 16. J Allergy Clin Immunol. 2011. PMID: 21762978 Free PMC article.
145 results