Fennell DA - Search Results

1

SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma.

Crawford N, Stasik I, Holohan C, Majkut J, McGrath M, Johnston PG, Chessari G, Ward GA, Waugh DJ, Fennell DA, Longley DB. Crawford N, et al. Among authors: fennell da. Cell Death Dis. 2013 Jul 18;4(7):e733. doi: 10.1038/cddis.2013.258. Cell Death Dis. 2013. PMID: 23868066 Free PMC article.

2

Dynamical systems analysis of mitochondrial BAK activation kinetics predicts resistance to BH3 domains.

Grills C, Crawford N, Chacko A, Johnston PG, O'Rourke F, Fennell DA. Grills C, et al. Among authors: fennell da. PLoS One. 2008 Aug 22;3(8):e3038. doi: 10.1371/journal.pone.0003038. PLoS One. 2008. PMID: 18725943 Free PMC article.

3

Machine vision based stochastic analysis of cancer cell mitochondrial dysfunction induced by a BH3 domain.

Chacko AD, Crawford NT, Johnston PG, Fennell DA. Chacko AD, et al. Among authors: fennell da. Apoptosis. 2008 Nov;13(11):1386-93. doi: 10.1007/s10495-008-0262-1. Apoptosis. 2008. PMID: 18814032

4

Combined inhibition of FLIP and XIAP induces Bax-independent apoptosis in type II colorectal cancer cells.

Wilson TR, McEwan M, McLaughlin K, Le Clorennec C, Allen WL, Fennell DA, Johnston PG, Longley DB. Wilson TR, et al. Among authors: fennell da. Oncogene. 2009 Jan 8;28(1):63-72. doi: 10.1038/onc.2008.366. Epub 2008 Sep 29. Oncogene. 2009. PMID: 18820704

5

Src and ADAM-17-mediated shedding of transforming growth factor-alpha is a mechanism of acute resistance to TRAIL.

Van Schaeybroeck S, Kelly DM, Kyula J, Stokesberry S, Fennell DA, Johnston PG, Longley DB. Van Schaeybroeck S, et al. Among authors: fennell da. Cancer Res. 2008 Oct 15;68(20):8312-21. doi: 10.1158/0008-5472.CAN-07-6736. Cancer Res. 2008. PMID: 18922903 Free PMC article.

6

Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing.

Wilson TR, Redmond KM, McLaughlin KM, Crawford N, Gately K, O'Byrne K, Le-Clorrenec C, Holohan C, Fennell DA, Johnston PG, Longley DB. Wilson TR, et al. Among authors: fennell da. Cell Death Differ. 2009 Oct;16(10):1352-61. doi: 10.1038/cdd.2009.76. Epub 2009 Jun 19. Cell Death Differ. 2009. PMID: 19543235

7

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8.

Chacko AD, Liberante F, Paul I, Longley DB, Fennell DA. Chacko AD, et al. Among authors: fennell da. BMC Cancer. 2010 Jul 20;10:380. doi: 10.1186/1471-2407-10-380. BMC Cancer. 2010. PMID: 20646307 Free PMC article.

8

Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis.

Crawford N, Chacko AD, Savage KI, McCoy F, Redmond K, Longley DB, Fennell DA. Crawford N, et al. Among authors: fennell da. Apoptosis. 2011 Mar;16(3):311-20. doi: 10.1007/s10495-010-0561-1. Apoptosis. 2011. PMID: 21107700

9

Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK.

McCoy F, Hurwitz J, McTavish N, Paul I, Barnes C, O'Hagan B, Odrzywol K, Murray J, Longley D, McKerr G, Fennell DA. McCoy F, et al. Among authors: fennell da. Cell Death Dis. 2010 Dec 16;1(12):e108. doi: 10.1038/cddis.2010.86. Cell Death Dis. 2010. PMID: 21368880 Free PMC article.

10

Polyomavirus enhancer activator 3 protein promotes breast cancer metastatic progression through Snail-induced epithelial-mesenchymal transition.

Yuen HF, Chan YK, Grills C, McCrudden CM, Gunasekharan V, Shi Z, Wong AS, Lappin TR, Chan KW, Fennell DA, Khoo US, Johnston PG, El-Tanani M. Yuen HF, et al. Among authors: fennell da. J Pathol. 2011 May;224(1):78-89. doi: 10.1002/path.2859. Epub 2011 Mar 14. J Pathol. 2011. PMID: 21404275

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