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Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses.
O'Brien A, Loftus RM, Pisarska MM, Tobin LM, Bergin R, Wood NAW, Foley C, Mat A, Tinley FC, Bannan C, Sommerville G, Veerapen N, Besra GS, Sinclair LV, Moynagh PN, Lynch L, Finlay DK, O'Shea D, Hogan AE. O'Brien A, et al. Among authors: bergin r. J Immunol. 2019 Jun 15;202(12):3404-3411. doi: 10.4049/jimmunol.1801600. Epub 2019 May 10. J Immunol. 2019. PMID: 31076528
Metabolic dysfunction mediated by HIF-1α contributes to epithelial differentiation defects in eosinophilic esophagitis.
Ryan S, Crowe L, Almeida Cruz SN, Galbraith MD, O'Brien C, Hammer JA, Bergin R, Kellett SK, Markey GE, Benson TM, Fagan O, Espinosa JM, Conlon N, Donohoe CL, McKiernan S, Hogan AE, McNamee EN, Furuta GT, Menard-Katcher C, Masterson JC. Ryan S, et al. Among authors: bergin r. J Allergy Clin Immunol. 2024 Dec;154(6):1472-1488. doi: 10.1016/j.jaci.2024.07.030. Epub 2024 Aug 27. J Allergy Clin Immunol. 2024. PMID: 39209164 Free article.
Glycogen-fuelled metabolism supports rapid mucosal-associated invariant T cell responses.
Cassidy FC, Kedia-Mehta N, Bergin R, Woodcock A, Berisha A, Bradley B, Booth E, Jenkins BJ, Ryan OK, Jones N, Sinclair LV, O'Shea D, Hogan AE. Cassidy FC, et al. Among authors: bergin r. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2300566120. doi: 10.1073/pnas.2300566120. Epub 2023 Jun 12. Proc Natl Acad Sci U S A. 2023. PMID: 37307453 Free PMC article.
66 results