Apostolatos A - Search Results

1

Protein kinase C δ (PKCδ) splice variants modulate apoptosis pathway in 3T3L1 cells during adipogenesis: identification of PKCδII inhibitor.

Patel R, Apostolatos A, Carter G, Ajmo J, Gali M, Cooper DR, You M, Bisht KS, Patel NA. Patel R, et al. Among authors: apostolatos a. J Biol Chem. 2013 Sep 13;288(37):26834-46. doi: 10.1074/jbc.M113.482638. Epub 2013 Jul 31. J Biol Chem. 2013. PMID: 23902767 Free PMC article.

2

Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35.

Apostolatos H, Apostolatos A, Vickers T, Watson JE, Song S, Vale F, Cooper DR, Sanchez-Ramos J, Patel NA. Apostolatos H, et al. Among authors: apostolatos a. J Biol Chem. 2010 Aug 20;285(34):25987-95. doi: 10.1074/jbc.M110.100735. Epub 2010 Jun 14. J Biol Chem. 2010. PMID: 20547768 Free PMC article.

3

Insulin promotes neuronal survival via the alternatively spliced protein kinase CδII isoform.

Apostolatos A, Song S, Acosta S, Peart M, Watson JE, Bickford P, Cooper DR, Patel NA. Apostolatos A, et al. J Biol Chem. 2012 Mar 16;287(12):9299-310. doi: 10.1074/jbc.M111.313080. Epub 2012 Jan 24. J Biol Chem. 2012. PMID: 22275369 Free PMC article.

4

Protein kinase C delta (PKCδ) splice variant modulates senescence via hTERT in adipose-derived stem cells.

Carter G, Patel R, Apostolatos A, Murr M, Cooper DR, Patel NA. Carter G, et al. Among authors: apostolatos a. Stem Cell Investig. 2014 Jan 19;1:3. doi: 10.3978/j.issn.2306-9759.2014.01.02. eCollection 2014. Stem Cell Investig. 2014. PMID: 27358850 Free PMC article.

5

Identification of a novel antiapoptotic human protein kinase C delta isoform, PKCdeltaVIII in NT2 cells.

Jiang K, Apostolatos AH, Ghansah T, Watson JE, Vickers T, Cooper DR, Epling-Burnette PK, Patel NA. Jiang K, et al. Among authors: apostolatos ah. Biochemistry. 2008 Jan 15;47(2):787-97. doi: 10.1021/bi7019782. Epub 2007 Dec 20. Biochemistry. 2008. PMID: 18092819

6

Dysregulated Alternative Splicing Pattern of PKCδ during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes.

Carter G, Apostolatos A, Patel R, Mathur A, Cooper D, Murr M, Patel NA. Carter G, et al. Among authors: apostolatos a. ISRN Obes. 2013 Apr 10;2013:161345. doi: 10.1155/2013/161345. eCollection 2013. ISRN Obes. 2013. PMID: 24533217 Free PMC article.

7

Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis.

Ratnayake WS, Apostolatos AH, Ostrov DA, Acevedo-Duncan M. Ratnayake WS, et al. Among authors: apostolatos ah. Int J Oncol. 2017 Nov;51(5):1370-1382. doi: 10.3892/ijo.2017.4131. Epub 2017 Sep 22. Int J Oncol. 2017. PMID: 29048609 Free PMC article.

8

Inhibition of atypical protein kinase C‑ι effectively reduces the malignancy of prostate cancer cells by downregulating the NF-κB signaling cascade.

Apostolatos AH, Ratnayake WS, Win-Piazza H, Apostolatos CA, Smalley T, Kang L, Salup R, Hill R, Acevedo-Duncan M. Apostolatos AH, et al. Int J Oncol. 2018 Nov;53(5):1836-1846. doi: 10.3892/ijo.2018.4542. Epub 2018 Aug 28. Int J Oncol. 2018. PMID: 30226591 Free PMC article.

9

Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypes.

Smalley T, Islam SMA, Apostolatos C, Apostolatos A, Acevedo-Duncan M. Smalley T, et al. Among authors: apostolatos a. Oncol Lett. 2019 Feb;17(2):1537-1546. doi: 10.3892/ol.2018.9792. Epub 2018 Dec 4. Oncol Lett. 2019. PMID: 30675210 Free PMC article.

10

Preclinical testing of 5-amino-1-((1R,2S,3S,4R)-2,3-dihydroxy-4-methylcyclopentyl)-1H-imidazole-4-carboxamide: a potent protein kinase C-ι inhibitor as a potential prostate carcinoma therapeutic.

Apostolatos AH, Apostolatos CA, Ratnayake WS, Neuger A, Sansil S, Bourgeois M, Acevedo-Duncan M. Apostolatos AH, et al. Anticancer Drugs. 2019 Jan;30(1):65-71. doi: 10.1097/CAD.0000000000000694. Anticancer Drugs. 2019. PMID: 30204596 Free PMC article.

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